L.I. ZHMAEVA^1, 2, E.N. SEREBRYAKOVA²

 ¹Children’s City Clinical Polyclinic no. 1, Chelyabinsk

²South-Ural State Medical University, Chelyabinsk

Contact details:

Zhmaeva L.I. — pediatrician, Assistant Lecturer of the Department of Hospital Pediatrics

Address: 25 Khudyakov St., Chelyabinsk, Russian Federation, 454080, tel.: +7-961-783-37-57, e-mail: liliya_khamitova-medicine@mail.ru

The SARS-CoV-2 pandemic has made a negative impact on the healthcare sector; it influenced the socio-economic state and worsened the quality of life in the country and all over the world. The purpose is to assess the clinical course of the new coronavirus infection in children living in Chelyabinsk and describe the possible pathological changes in their organs and systems during 6 months after SARS-CoV-2 infection.

Material and methods. The patients were examined at Children’s City Clinic no. 1 in Chelyabinsk. The prospective study by continuous sampling method included 158 children (75 girls, 83 boys). SARS-CoV-2 infection was identified by PCR with reverse transcription in April 2020 — May 2022. The clinical symptoms were studied; the children’s health status was assessed during 6 months after the SARS-CoV-2 detection.

Results. The most common clinical implication of SARS-CoV-2 in children was catarrhal respiratory syndrome. The mild form of new coronavirus infection was registered in 92 children, the moderate form in 56 children. The asymptomatic form of this infection was found in 10 children. The most frequent change in the children’s health status within 6 months after SARS-CoV-2 infection was asthenic syndrome in 36 children.

Conclusions. The most common change in health status within 6 months of observation in children was asthenic syndrome (23%) with the average duration of 2 months.

Key words: new coronavirus infection, children, asthenic syndrome.

REFERENCES

1. Namazova-Baranova L.S. Coronavirus infection (COVID-19) in children (as of June 2020). Pediatricheskaya farmakologiya, 2020, no. 17 (3) (in Russ.). DOI: 10.15690/pf.v17i3.2121
2. Aleksandrovich Yu.S., Baybarina E.N., Baranov A.A. et al. Management of children with a disease caused by a new coronavirus infection (SARS-CoV-2). Pediatricheskaya farmakologiya, 2020, no. 17 (2), pp. 103–118 (in Russ.). DOI: 10.15690/ pf.v17i2.2096
3. Starshinova A.A., Kushnareva E.A., Malkova A.M. et al. New coronavirus infection: features of the clinical course, the possibility of diagnosis, treatment and prevention of infection in adults and children. Voprosy sovremennoy pediatrii, 2020, no. 19 (2), pp. 123–131 (in Russ.). DOI: 10.15690/vsp.v19i2.2105
4. Belan Yu.B., Gashina E.A., Lobova E.F. et al. Coronavirus infection in children in the Omsk region. Detskie infektsii, 2020, no. 19 (4), pp. 30–33 (in Russ.). DOI: 10.22627/2072-8107-2020-19-4-30-33
5. Moskaleva E.V., Petrova A.G., Rychkova L.V. et al. Status of immune status indicators in children after a new coronavirus infection. Acta biomedica scientifica, 2021, no. 6 (2), pp. 58–62 (in Russ.). DOI: 10.29413/ABS.2021-6.2.6
6. Martynova G.L., Stroganova M.A., Bogvilene Ya.A. et al. Clinical and epidemiological features of the new coronavirus infection COVID-19 in children of Krasnoyarsk. Lechenie i profilaktika, 2021, vol. 11, no. 1, pp. 5–12 (in Russ.).
7. Meskina E.R. Preliminary clinical and epidemiological analysis of the first 1000 cases of COVID-19 in children in the Moscow region. Zhurnal mikrobiologii, epidemiologii i immunobiologii, 2020, no. 97 (3), pp. 202–215 (in Russ.). DOI: 10.36233/0372-9311-2020-97-3-2
8. Meskina E.R., Khadisova M.K., Stashko T.V. et al. New coronavirus infection in children in the Moscow region: clinical, epidemiological and therapeutic aspects. Al’manakh klinicheskoy meditsiny, 2021, no. 49 (3), pp. 207–218 (in Russ.). DOI: 10.18786/2072-0505-2021-49-032
9. Shakmaeva M.A., Chernova T.M., Timchenko V.N. et al. Peculiarities of a new coronavirus infection in children of different ages. Detskie infektsii, 2021, no. 20 (2), pp. 5–9 (in Russ.). DOI: 10.22627/2072-8107-2021-20-2-5-9
10. Medvedev V.E., Frolova V.I., Gushanskaya E.V. et al. Asthenic disorders within the post-covid syndrome. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2021, no. 121 (4), pp. 152–158 (in Russ.). DOI: 10.17116/jnevro2021121041152
11. Ludvigsson J.F. Case report and systematic review suggest that children may experience similar long-term effects to adults after clinical COVID-19. Acta Paediatr, 2021, vol. 110 (3), pp. 914–921. DOI: 10.1111/apa.15673 Epub 2020 Dec 3.