R.G. ESIN^{1, 2}, D.E. ERKINOVA¹, A.F. FATYKHOVA¹, L.R. ALIMBEKOVA¹

 ¹Kazan (Volga) Federal University, Kazan

²Kazan State Medical Academy — Branch Campus of the FSBEI FPE RMACPE MOH Russia, Kazan

 Contact details:

Esin R.G. — MD, Professor of the Department of Neurology, Professor of the Department of Neurology with a course in Psychiatry, Psychology and Medical Genetics

Address: 1a Chekhova St., 420012 Kazan, Russian Federation, tel.: +7 (843) 233-30-80, e-mail: radyesin@mail.ru

The article presents a review of the literature on the pathogenesis of Guillain — Barré syndrome, its association with herpes viruses, modern diagnostic and treatment principles, including plasmapheresis and immunoglobulins. Diagnosis of the disease is clinical, but in complex cases it is necessary to assess the titers of specific IgG and IgM in the blood serum and cerebrospinal fluid or determine the virus DNA in the cerebrospinal fluid. Treatment includes immunoglobulins, plasmapheresis, and antiviral drugs (acyclovir, valacyclovir, famciclovir). Currently, 39 cases Guillain-Barre syndrome association of with the varicella zoster virus are described. The authors provide their own observations with complete recovery of severe tetraparesis.

Key words: Guillain — Barré syndrome, varicella zoster virus, clinical case.

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