L.I. FEYSKHANOVA¹, A.A. NIGMATYANOVA¹, Yu.M. BOYCHUK¹, N.R. KHARISOVA¹, A.V. MAKSIMOV²

¹Kazan State Medical University, 49 Butlerov Str., Kazan, Russian Federation, 420012

²Republic Clinical Hospital of the MH of RT, 138 Orenburgskiy Trakt, Kazan, Russian Federation, 420064

 Feyskhanova L.I. ― Cand. Med. Sc., Associate Professor of the Department of Hospital Therapy, tel. +7-917-275-21-66, e-mail: ljuts@rambler.ru

Nigmatyanova A.A. ― postgraduate student of the Department of Hospital Therapy, tel. +7-987-277-60-39, e-mail: anzilya-s@yandex.ru

Boychuk Yu.M. ― student of Therapeutic Faculty, tel. +7-951-065-94-41, e-mail: lipatovayulia1994@yandex.ru

Kharisova N.R. ― student of Therapeutic Faculty, tel. +7-953-484-85-01, e-mail: nailya94@bk.ru

Maksimov A.V. ― D. Med. Sc., Head of the Department of Vascular Surgery №1, tel. +7-987-098-76-34, e-mail: sosudik_service@mail.com

Ankylosing spondylitis is a disease characterized by lesions of the musculoskeletal system, with the possible involvement of other organs and systems; in particular, it is often accompanied by cardiovascular disease. Ankylosing spondylitis is more common in men, in this connection the the aim of our research was to identify the gender characteristics of cardiovascular lesions in patients with ankylosing spondylitis. The study involved 99 patients, 71 men and 28 women who underwent echocardiography, measurement of the QT interval dispersion on electrocardiography and ankle-brachial index. The results obtained when comparing groups of men and women revealed that in men there is a relationship between the activity of ankylosing spondylitis and diastolic dysfunction of the heart, which, in turn, is accompanied by reduced blood flow in the peripheral vessels. At the same time, in women suffering from ankylosing spondylitis, we found a correlation between functional changes and reduced ejection fraction of the left ventricle, diastolic dysfunction, impaired blood flow in peripheral vessels and increased myocardial electrical instability.

Key words: ankylosing spondylitis, gender features, electrical instability of myocardium, diastolic dysfunction.

REFERENCES

1. Rebrov A.P., Gaydukova I.Z., Poddubnyy D.A. Cardiovascular pathology in patients with ankylosing spondylitis. Nauchno-prakticheskaya revmatologiya, 2012, no. 2, pp. 100-105 (in Russ.).
2. Nigmat’yanova A.A., Feyskhanova L.I., Abdrakipov R.Z., Khasanov R.M. A case of severe complicated ankylosing spondylitis. Prakticheskaya meditsina, 2016, vol. 2, no. 4 (96), pp. 82-84 (in Russ.).
3. Mashina T.V., Golukhova E.Z. Diastolic dysfunction of the left ventricle in patients with atrial fibrillation: pathogenetic mechanisms and modern ultrasound evaluation methods (analytical review). Kreativnaya kardiologiya, 2014, no. 4, pp. 43-52 (in Russ.).
4. Chasnoyt’ A.R. Dispersion of the QT interval and its diagnostic value in assessing the state of the myocardium. Zdravookhranenie, 2002, no. 8, pp. 56-59 (in Russ.).
5. Rogoza A.N. The role and capabilities of the ankle-brachial index of systolic pressure in preventive examinations. RMZh, 2011, no. 4, p. 173 (in Russ.).