V.M. DELYAGIN, M.B. MELNIKOVA, B.S. PERSHIN, G.I. SERIK, D.T. DZHANDAROVA

Federal Scientific and Clinical Centre of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 1 Samori Maschel St., Moscow, Russian Federation, 117997 

Delyagin V.M. — D. Med. Sc., Professor, Head of the Department of Functional Diagnostics, Head of the Department of Clinical Physiology, tel. (495) 287-65-70 (ext. 48-09), e-mail: delyagin-doktor@yandex.ru

Melnikova M.B. — Cand. Med. Sc., ophthalmologist, tel. (495) 287-65-70 (ext. 12-13), e-mail: Marina-del@yandex.ru

Pershin B.S. — ophthalmologist, tel. (495) 287-65-70 (ext. 12-13), e-mail: Boris.Pershin@fccho-moscow.ru

Serik G.I. — postgraduate student of the Department of Clinical Physiology, tel. (495) 287-65-70 (ext. 12-13), e-mail: serikgi@yandex.ru

Dzhandarova D.T. — Cand. Biol. Sc., Head of Bacteriology Laboratory, tel. (495) 287-65-70 (ext. 13-30), e-mail: Dzhamilya.Dzhandarova@fccho-moscow.ru

Basing on own observations and literature data, we present pathophysiology, epidemiology, diagnosis and treatment of eye fungal infections. Eye fungal infection is typical in cases of congenital and acquired immunodeficiencies, it is likely with cancer, neutropenia ≤500/ml, with antibiotic-resistant fever of unknown origin, heavy surgery, intravenous nutrition, blood concentrations of β-d-glucan ≥20 pg. The outcome of fungal endophthalmitis depends on the virulence of the organism, involving intraocular media latitude, time and type of intervention. Infection associated with mold fungi is worse than the one associated with yeast. Aspergillosis predominantly affects the yellow spot. We discuss the clinical and instrumental pattern, emphasizing the importance of ultrasound examination. Recommendations are given on the treatment and follow-up of patients.

Key words: eye, fungal infection, children

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