E.L. SOROKIN^1,2, S.Yu. AVRAMENKO³, A.A. KALASHNIKOV³, O.V. PYATYSHINA², R.A. BURYA², V.Ya. KOSTIV²

¹Khabarovsk branch of S. Fyodorov Eye Microsurgery Federal State Institution, 211 Tikhookeanskaya Str., Khabarovsk, Russian Federation, 680033

²Far-Eastern State Medical University, 35 Muraviev-Amurskii Str., Khabarovsk, Russian Federation, 680000

³City Clinical Hospital №10, 213 Tikhookeanskaya Str., Khabarovsk, Russian Federation, 680033

  Sorokin E.L. ― D. Sc. (medicine), Professor, Deputy Director on Scientific Work, Professor of the General and Clinical Surgery Department, tel. (4212) 72-27-92, e-mail: naukakhvmntk@mail.ru

Avramenko S.Yu. ― Head of the Ophthalmology Department, tel. (4212) 72-27-92, e-mail: naukakhvmntk@mail.ru

Kalashnikov A.A. ― Chief Doctor, tel. (4212) 72-27-92, e-mail: naukakhvmntk@mail.ru

Pyatyshina O.V. ― PhD (medicine), Associate Professor of the General and Clinical Surgery Department, tel.: +7 (4212) 72-27-92, e-mail: naukakhvmntk@mail.ru

Burya R.A. ― resident of the Ophthalmology Course at the General and Clinical Surgery Department, tel. (4212) 72-27-92, e-mail: naukakhvmntk@mail.ru

Kostiv V.Ya. ― PhD (medicine), Associate Professor of the General and Clinical Surgery Department, tel. (4212) 72-27-92, e-mail: naukakhvmntk@mail.ru

 The research objective was to study the frequency of anterior uveitis, their etiology and outcomes in adult residents of the Khabarovsk Region. A continuous sample of all cases of endogenous anterior uveitis in adult patients of the Khabarovsk Region from 2010 to 2016 was conducted. The total number of cases of anterior uveitis in this period was 2264 people, i.e. 40.8% of all cases of inflammatory pathology of the anterior segment of the eye in this study. In 578 people, the clinical course of anterior uveitis was acute (26.7%), in 1593 people ― recurrent, chronic (73.3%). In 23% of patients with chronic course of anterior uveitis, etiology was determined: the majority had systemic rheumatic pathology, foci of focal infection. In 77% of patients with recurrent course of uveitis, its etiology was not identified. The main etiological cause of recurrent course of anterior uveitis in this research is rheumatoid systemic pathology (65%). In diagnosis and treatment of anterior uveitis, close cooperation between ophthalmologists and rheumatologists is necessary.

Key words: endogenous anterior uveitis, recurrent course, rheumatoid systemic pathology, complications of uveitis.

(For citation: Sorokin E.L., Avramenko S.Yu., Kalashnikov A.A., Pyatyshina O.V., Burya R.A., Kostiv V.Ya. Frequency of recurrent forms of endogenous uveitis, ways to improve their etiological diagnosis and treatment. Practical Medicine. 2018)

REFERENCES

1. Arben’eva N.S., Bratko V.I., Gorbenko O.M. et al. The activity of the local immunoinflammatory process in the pathogenesis of autoimmune uveitis. Allergologiya i immunologiya, 2017, vol. 18, no. 2, pp. 97-100 (in Russ.).
2. Godzenko A.A., Razumova I.Yu. Uveitis and spondyloarthropathies. Nauchno-prakticheskaya revmatologiya, 2005, no. 6, pp. 63-69 (in Russ.).
3. Demina A.B., Dubinina T.V., Erdes Sh.F. NLA-B27-associated uveitis: from pathogenesis to therapy. Sovremennaya revmatologiya, 2015, vol. 9, no. 4, pp. 98-105 (in Russ.).
4. Drozdova E.A. Uveit pri revmaticheskikh zabolevaniyakh: osobennosti kliniki, diagnostika, immunopatogenez i lechenie: avtoref. dis. … dokt. med. nauk [Uveitis in rheumatic diseases: features of the clinic, diagnosis, immunopathogenesis and treatment. Synopsis of dis. Dr med. sci]. Chelyabinsk, 2006. 46 p.
5. Pavlyuchenko K.P., Pavlyuchenko A.K., Sinyachenko O.V. Uveitis with arthritis. Oftal’mologicheskiy zhurnal, 2012, no. 3 (446), pp. 57-60 (in Russ.).
6. Panova I.E., Teplova S.N., Lapina E.B. et al. Rear toxoplasmosis uveitis: clinical characteristics, immunological features of pathogenesis. Oftal’mologicheskie vedomosti, 2009, vol. 2, no. 3, pp. 4-10 (in Russ.).
7. Moiseev S.V. Uveitis in rheumatologist practice: the role of inhibitors of tumor necrosis factor. Sovremennaya revmatologiya, 2009, no. 4, pp. 76-81 (in Russ.).
8. Drozdova E.A., Yadykina E.V., Patlasova L.A. Analysis of the incidence and severity of complications in rheumatic uveitis. RMZh. Klinicheskaya oftal’mologiya, 2013, no. 1, pp. 2-4 (in Russ.).
9. Smolyakova G.P., Aktasheva E.L. Dinamika struktury zabolevaemosti endogennymi uveitami v Khabarovskom krae [Dynamics of the structure of the incidence of endogenous uveitis in the Khabarovsk Krai]. Aktual’nye problemy oftal’mologii: mat-ly konf. Blagoveshchensk, 1997. Pp. 223-225.
10. Yuldasheva S.A., Karim-Zade Kh.D., Satorov S. Modern view on the etiology, pathogenesis and prevalence of uveitis. Vestnik Avitsenny, 2015, no.1, p. 141 (in Russ.).
11. Birnbaum A.D., Little D.M., Tessler H.H., Goldstein D.A. Etiologies of chronic anterior uveitis at a tertiary referral center over 35 years. Ocular Immunology & Inflammation, 2011, vol. 19, no. 1, pp. 19-24.
12. Hamade I.H., Elkum N., Tabbara Kh.F. Causes of uveitis at a referral center in Saudi Arabia. Ocular Immunology and Inflammation, 2009, vol. 17, no. 1, pp. 11-16.