P.А. LEBEDEV¹, I.В. MALOV¹, Е.S. PSHENITSYNA¹, L.G. SENNOVА¹, Е.V. BAUKINA¹, V.N. GRISHANOV², D.V. KORNILIN², А.S. CHEBOTAREV², М.V. KOMAROVА², V.P. ZAKHAROV²

¹Samara State Medical University, 89 Chapaevskaya Str., Samara, Russian Federation, 443099

²Samara National Research University named after S.P. Korolev, 34 Moskovskoe highway, Samara, Russian Federation, 443086

 Contact:

Lebedev P.A. ― D. Med. Sc., Head of the Therapy Department, e-mail: lebedcard@rambler.ru

Malov I.V. ― D. Med. Sc., Head of the Department of Eye Diseases, tel. (846) 956-52-44, e-mail: ivmsamara@gmail.com

Pshenitsina E.S. ― Cand. Med. Sc., Associate Professor of the Department of Eye Diseases, tel. (846) 956-52-44, e-mail: pshenicina@gmail.com

Sennova L.G. ― Cand. Med. Sc., Associate Professor of the Department of Eye Diseases, tel. (846) 956-52-44, e-mail: ipokgb@mail.com

Baukina E.V. ― Resident Physician of the Department of Internal Medicine, e-mail: lebedcard@rambler.ru

Grishanov V.N. ― Cand. Tech. Sc., Associate Professor of the Department of Laser and Biotechnical Systems, e-mail: vladgrishanov@yandex.ru

Kornilin D.V. ― Cand. Tech. Sc., Associate Professor of the Department of Laser and Biotechnical Systems, tel. (848) 267-45-50, e-mail: vladgrishanov@yandex.ru

Chebotarev A.S. ― Master’s Degree Student of the Department of Laser and Biotechnical Systems, tel. (848) 267-45-50, e-mail: vladgrishanov@yandex.ru

Komarova M.V. ― Cand. Tech. Sc., Associate Professor of the Department of Laser and Biotechnical Systems, tel. (848) 267-45-50, e-mail: vladgrishanov@yandex.ru

Zakharov V.P. ― D. Phys. and Math. Sc., Head of the Department of Laser and Biotechnical Systems, tel. (848) 267-45-50, e-mail: vladgrishanov@yandex.ru

The paper is devoted to the study of the relationship between skin autofluorescence caused by the accumulation of advanced glycation endproducts (AGEs) and age-related macular degeneration (ARMD), and cataract. The study revealed a significant increase in the AF parameter in patients with ARMD: 0.154±0.005, p<0.008 in comparison with the control group: 0.125±0,004 and patients with cataract: 0.127±0.009. The authors consider that this method has a perspective as a screening one, the results of which can increase the predictable value of the approach based on the evaluation of ARMD risk factors.

Key words: skin autofluorescence (AF), advanced glycation endproducts (AGEs), age-related macular degeneration (ARMG), wet, cataract.

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