Features of the physical and mental development of children of the first year of life, born to women with fetoplacental insufficiency
E.M. IUTINSKIY, S.A. DVORYANSKIY, V.V. OVCHINNIKOV
Kirov State Medical Academy, 112 K. Marks St., Kirov, Russian Federation, 610027
Iutinskiy E.M. — Cand. Med. Sc., Associate Professor of the Department of Obstetrics and Gynecology, tel. (8332) 555-321, e-mail: dvorsa@mail.ru
Dvoryanskiy S.A. — D. Med. Sc., Head of the Department of Obstetrics and Gynecology, tel. (8332) 555-321, e-mail: dvorsa@mail.ru
Ovchinnikov V.V. — Cand. Med. Sc., Associate Professor of the Department of Obstetrics and Gynecology, tel. (8332) 555-321, e-mail: dvorsa@mail.ru
The article presents data on illnesses among children of the first year of life, born to women with fetoplacental insufficiency. A comparative assessment of efficiency of traditional pharmacological therapy of fetoplacental insufficiency and complex therapy with participation of medical ozone was carried out. In particular it is shown, that including in a complex of therapy of fetoplacental insufficiency the ozone-oxygen mixture promotes more effective elimination of hypoxia of a foetus and restoration of an adequate fetus and placental perfusion that is realised further by reduction of diseases in children of the first year of life.
Key words: pregnancy, fetoplacental insufficiency, ozone therapy.
REFERENCES
- Bassan H. The pregnant spontaneously hypertensive rat as a model of asymmetric intrauterine growth retardation and neurodevelopmental delay. Hypertens Pregnancy, 2013, vol. 24, no. 3, pp. 201-211.
- Sidorova I.S., Makarov I.O. Kliniko-diagnosticheskie aspekty fetoplatsentarnoy nedostatochnosti [Clinical diagnostic aspects of placental insufficiency]. Moscow: MIA, 2005. 295 p.
- Duttaroy A.K. Transport of fatty acids across the human placenta: a review. Prog Lipid Res., 2014, vol. 48, no. 1, pp. 52-61.
- Hodgin J.B., Rasoulpour M., Markowitz G.S., D’Agati V.D. Very low birth weight is a risk factor for secondary focal segmental glomerulosclerosis. Clin J Am Soc Nephrol., 2012, vol. 4, no. 1, pp. 71-76.
- Roos S., Kanai Y., Prasad P.D. et al. Regulation of placental amino acid transporter activity by mammalian target of rapamycin. Am J Physiol Cell Physiol., 2009, vol. 296, no. 1, pp. 142-150.
- Germani D., Puglianiello A. et al. Uteroplacental insufficiency down regulates insulin receptor and affects expression of key enzymes of long-chain fatty acid (LCFA) metabolism in skeletal muscle at birth. Cardiovasc Diabetol., 2014, vol. 18, p. 14.
- Li C.S., Loch-Caruso R. Sodium arsenite inhibits migration of extravillous trophoblast cells in vitro. Reprod Toxicol., 2014, vol. 24, no. 3-4, pp. 296-302.
- Rees S., Inder T. Fetal and neonatal origins of altered brain development. Early Hum Dev., 2013, vol. 81, no. 9, pp. 753-761.
- Ke X. Nonresponsiveness of cerebral p53-MDM2 functional circuit in newborn rat pups rendered IUGR via uteroplacental insufficiency. Am J Physiol Regul Integr Comp Physiol., 2014, vol. 288, no. 4, pp. 1038-1045.
- La Marca, B.D. Pathophysiology of hypertension in response to placental ischemia during pregnancy: a central role for endothelin? Gend Med., 2012, vol. 5, rr. 133-138.