Features of cerebral venous hemodynamics in acute cerebrovascular accidents
M.M. YULDASHEVA1, 2, E.N. MAZHIDOVA2, B.G. GAPHUROV3, Zh.A. NAZAROVA3, O.B. DORONINA1, B.M. DORONIN1
1Novosibirsk State Medical University of the Ministry of Health of the Russian Federation, Novosibirsk
2Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan
3Tashkent Institute of Advanced Medical Education, Tashkent, Uzbekistan
Contact details:
Yuldasheva M.M. — postgraduate student of the Department of Neurology, Pediatric Neurology and Medical Genetics, senior assistant of the Department of Neurology
Address: 52 Krasniy prospect, Novosibirsk, Russian Federation, 630091, tel.: +7-913-702-03-03, e-mail: manzura.yuldasheva.2017@mail.ru
282 patients from the neurological department of the somatic hospital of the city of Tashkent from 2015 to 2018 were examined with a diagnosis of ischemic stroke (II) in the basin of the internal carotid artery of moderate severity (without impaired consciousness) in the early recovery phase.
Results. In 237 patients, based on questionnaires, rheoencephalography, and duplex scanning, venous cerebral dysfunction (VCD) of various degrees was revealed, correlating with the severity of cognitive impairment, decreased memory, and emotional response. An inversely proportional relationship between the severity of VCD and the speed of blood flow in the main extra- and intracranial arteries was also revealed. The second stage of study is the effect of veinprotective health aids on the quality of life and rehabilitation of patients after ischemic stroke in the presence of VCD.
Conclusion. Positive results were obtained, which allows recommending such drugs for use in clinical practice.
Key words: ischemic stroke, venous cerebral dysregulation, neurologic impairment.
(For citation: Yuldasheva M.M., Mazhidova E.N., Gaphurov B.G., Nazarova Zh.A., Doronina O.B., Doronin B.M. Features of cerebral venous hemodynamics in acute cerebrovascular accidents. Practical Medicine. 2019. Vol. 17, № 7, P. 111-116)
REFERENCES
- Seifert H.A., Pennypacker K.R. Molecular and cellular immune responses to ischemic brain injury. Translational Stroke Research, 2014, vol. 5, pp. 543–553.
- Silva N.A., Sousa N., Reis R.L. et al. From basics to clinical: a comprehensive review on spinal cord injury. Progress in neurobiology, 2014, vol. 114, rr. 25-57.
- Tso M.K., Macdonald R.L. Acute microvascular changes after subarachnoid hemorrhage and transient global cerebral ischemia. Stroke research and treatment, 2013, pp. 11–18.
- Mursch K., Wachter A., Radke K. et al. Blood flow velocities in the basal vein after subarachnoid haemorrhage. A prospective study using transcranial duplex sonography. Acta Neurochir (Wien), 2001, vol. 143, pp. 793–799.
- Takahashi A., Ushiki T., Abe K. et al. Cytoarchitecture of periendothelial cells in human cerebral venous vessels as compared with the scalp vein. A scanning electron microscopic study. Archives of histology and cytology, 1994, vol. 57, pp. 331–339.
- Chen S., Chen Y., Xu L. et al. Venous system in acute brain injury: Mechanisms of pathophysiological change and function. Experim. Neurol, 2015, vol. 272, pp. 4–10.
- Kilic T., Akakin A. Anatomy of cerebral veins and sinuses. Frontiers of neurology and neuroscience, 2008, vol. 23, pp. 4-15.
- Yu W., Rives J., Welch B. et al. Hypoplasia or occlusion of the ipsilateral cranial venous drainage is associated with early fatal edema of middle cerebral artery infarction. Stroke, 2009, vol. 40, pp. 3736–3739.
- Lauw M.N., Barco S., Coutinho J.M. et al. Cerebral venous thrombosis and thrombophilia: a systematic review and meta-analysis. Semin Thromb Hemost, 2013, vol. 39, pp. 913–927.
- Li Q., Khatibi N., Zhang J.H. Vascular neural network: the importance of vein drainage in stroke. Translational Stroke Research, 2014, vol. 5, pp. 163–166.
- Semenov S.E., Kovalenko A.V., Moldavskaya I.V. et al. Diagnosis and the role of cerebral venous congestion during and outcomes of non-hemorrhagic stroke. Kompleksnye problemy serdechno-sosudistykh zabolevaniy, 2014, no. 3, pp. 108–117 (in Russ.).
- Gafurov B.G., Alikulova N.A., Nazarova Zh.A. Rol’ tserebral’noy venoznoy disgemii v formirovanii khronicheskoy nedostatochnosti mozgovogo krovoobrashcheniya [The role of cerebral venous dysgemia in the formation of chronic cerebrovascular insufficiency]. Fundamental’nye osnovy innovatsionnogo razvitiya nauki i obrazovaniya. Penza, 2019. Pp. 223–242.