L.YU. KULAGINA^1,2, I.R. VALIULLINA¹, E.R. KADYSEVA, A.A. SHIKALEVA²

 ¹Republic Clinical Hospital, Kazan

²Kazan State Medical Academy — Branch Campus of RMACPE MH Russia, Kazan

Contact details:

Kulagina L.Yu. — Head of the Clinical Pharmacology Department, Researcher of the Scientific-Research Department, Assistant Lecturer of the Department of Clinical Pharmacology and Pharmacotherapy

Address: 138 Orenburgskiy trakt, Kazan, Russian Federation, 420064, tel.: +7 (843) 231-20-66, e-mail: kazanfarm@yandex.ru

 Microbiological monitoring allows epidemiologists and clinical pharmacologists to control hospital-acquired infections and make timely strategic decisions.

The purpose — to determine the tendency of prevailing problem microflora and to develop a strategy of empirical antibacterial therapy for severe nosocomial infections and inflammatory processes.

Material and methods. The article analyzes the main groups of pathogens of hospital infections in dynamics for the first quarter of 2018, 2019 and 2020. The relation of positive cultures to the total number of investigated samples was taken for the analysis. Antibiotic sensitivity was isolated, identified and determined using conventional mass spectrometry methods.

The results. The stable sowing rate of Acinetobacter baumannii and Klebsiella pneumoniae in the intensive care and surgical departments was noted for the analyzed periods. To solve the problem of antibiotic resistance in the inpatient department, a strategy to contain it was developed.

Keywords: antibiotic resistance, resistant strains of microorganisms, microbiological monitoring, antibacterial therapy, epidemiological surveillance. 

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