Efficiency of antibiotic therapy optimization in patients with acute pancreatitis
A.M. ZAINUTDINOV, I.S. MALKOV
Kazan State Medical Academy, 36 Butlerov Str., Kazan, Russian Federation, 420012
Zainutdinov A.M. ― Cand. Med. Sc., Associate Professor of the Surgery Department, Head of Surgery Department №2, tel. +7-917-268-25-34, e-mail: zainoutdinov@mail.ru
Malkov I.S. ― D. Med. Sc., Professor, Head of the Surgery Department, tel. +7-965-594-40-07, e-mail: ismalkov@yahoo.com
Analysis of the results of antibiotic therapy in 58 patients with acute pancreatitis was performed. All patients with suppurative complications underwent operations. Omental and retroperitoneal abscesses were drained with low-invasive techniques (puncture drainage under US control), and the widely spread forms of infection were operated with traditional «open» techniques ― laparotomy, marsupialization, lumbotomy. The main group of patients consisted of 30 patients admitted to the clinic with aseptic pancreatic necrosis. In this group the patients received interstitial electrophoresis during 8±4 days. The comparison group consisted of 28 patients who received traditional conservative therapy. In the main group the clinical laboratory indication normalized by the 10th day, the suppurative complication reduced by 13%, and lethality reduced by 10% (15% in the comparison group).
Key words: acute pancreatitis, antibacterial therapy, laparoscopy.
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