G.S. MAKSHAKOV ^1-3, E.E. NEKRASHEVICH¹, O.V. USHAKOVA¹, M.V. SHUMILINA^1-3, E.P. EVDOSHENKO^1-3

¹City Clinical Hospital №31, City Center for Multiple Sclerosis and Other Autoimmune Diseases, 11 Dinamo Driveway, Saint Petersburg, Russian Federation, 197110

²Medical Association of Physicians and Centers for Multiple Sclerosis and Other Neuroimmunological Diseases, 20-22 Galernaya Str., lit. A, office 422, Saint Petersburg, Russian Federation, 190000

³First St. Petersburg State Medical University named after Acad. I.P. Pavlov, 6-8 Lva Tolstogo Str., Saint Petersburg, Russian Federation, 197022

 Makshakov G.S. ― Neurologist, postgraduate student of the Neurology Department, e-mail: g.makshakov@centrems.com, ORCID ID: 0000-0001-6831-0441

Nekrashevich E.E. ― Medical Psychologist, tel. (812) 235-20-45 e-mail: e.bikova@centrems.com, ORCID ID: 0000-0002-3334-2045

Ushakova O.V. ― Medical Psychologist, tel. (812) 235-20-45 e-mail: coalaps@mail.ru, ORCID ID: 0000-0003-0937-6971

Shumilina M.V. ― PhD (medicine), Head of the Center, Assistant of the Neurology Department, tel. (812) 235-20-45, e-mail: m.shumilina@centrems.com, ORCID ID: 0000-0001-7439-2690

Evdoshenko E.P. ― PhD (medicine), Head of the Center, tel. (812) 235-20-45, e-mail: e.evdoshenko@centrems.com, ORCID ID: 0000-0002-8006-237X

 Objective ― development and clinical approbation of methods for rehabilitation of cognitive functions in patients with multiple sclerosis.

Material and methods. 13 people were diagnosed with a relapsing-remitting multiple sclerosis, of which 5 men and 8 women, the average age ― 38.9±8.4 years. The indicators of short-term, long-term, mechanical and logical memory, mediated memorization, speed of information processing, anxiety and depression at the stage of inclusion, 1 and 4 months after the start of trainings, were evaluated. Two trainings to improve memory and attention were conducted with an interval of 1 week, patients were given daily homework for 1 week. This was followed by the observation phase of up to 4 months.

Results. After the performed rehabilitation procedures, an improvement in the indices of indirect memorization, various types of memory and information processing speed was observed, which persisted after 4 months from the start of trainings.

Key words: multiple sclerosis, cognitive rehabilitation, social cognitive training.

(For citation: Makshakov G.S., Nekrashevich E.E., Ushakova O.V., Shumilina M.V., Evdoshenko E.P. Effectiveness of cognitive rehabilitation in multiple sclerosis: experience of a pilot study. Practical Medicine. 2018)

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