Early diagnosis of critical congenital heart diseases in newborns with the use of NT-proBNP
V.T. SAIDOVA, D.R. SABIROVA, E.M. NEMIROVSKAYA, L.M. MIROLYUBOV
Children’s Republican Clinical Hospital of the
Ministry of Health of the Republic of Tatarstan, Kazan
Kazan State Medical Academy
Kazan State Medical University
Saidova Venera Talgatovna
external PhD student of the Department of Hospital Pediatrics
with a course of postgraduate education and polyclinic pediatrics
140 Orenburgskiy Trakt Str., Kazan 420138
tel. 8-919-685-66-84, e-mail: saidovavenera@gmail.com
Critical heart diseases in newborns are the congenital heart diseases whereby delivery of cardiac and surgery care is prescribed to be executed in the first days and sometimes in the first hours of life of a baby. The paper presents the diagnostic findings of 33 newborns with critical congenital heart diseases; is evaluated the feasibility of using N-terminal predecessor of brain natriuretic peptide (NT-proBNP) in neonatal screening for the diagnosis of critical cases of congenital heart diseases in the first days of life.
Key words: newborn, NT-pro-BNP, congenital heart defects.
REFERENCES
1. Prikaz Ministerstva zdravoohranenija i social’nogo razvitija Rossijskoj Federacii ot 1.06.2010 g. N 409n g. Moskva «Ob utverzhdenii Porjadka okazanija neonatologicheskoj medicinskoj pomoshhi» // Rossijskaja gazeta. — 2010. — № 5259.
2. Ginter E.K. Medicinskaja genetika: uchebnik. — M., 2003. — 448 s.
3. Sharykin A.S. Vrozhdennye poroki serdca. Rukovodstvo dlja pediatrov, kardiologov, neonatologov. — M.:, 2005. — 384 s.
4. Bespalova E. Diagnoz do rozhdenija / E. Bespalova // Med. gazeta. — 2009. — № 86.
5. Suhareva G.Je. Prenatal’naja diagnostika i postnatal’nye ishody vrozhdennoj patologii serdechno-sosudistoj sistemy u detej // Materialy konferencii «Novye tehnologii v pediatricheskoj nauke, praktike i obrazovanii» 8-9 aprelja 2010 g. — Odessa, 2010. — S. 44.
6. Januzzi J.L. Natriuretic peptide testing: A window into the diagnosis and prognosis of heart failure // Cleveland. Clin J Med. — 2006. — № 73. — P. 149-157.
7. Nir A., Lindinger A., Rauh M. et al. NT-proB-type natriuretic peptide in infants and children: reference values based on combined data from four studies // B Pediatr Cardiol. — 2009. — № 30. — P. 3-8.
8. Zatikjan E.P. Real’nye vozmozhnosti jehokardiograficheskoj diagnostiki koarktacii aorty u ploda // Akusherstvo i ginekologija. — 2012. — № 8. — S. 51-55.
9. Miroljubov L.M. Vrozhdennye poroki serdca u novorozhdennyh i detej pervogo goda zhizni / L.M. Miroljubov. — Kazan’: Medicina, 2008. — 152 s.
10. «Neonatal’nyj skrining s cel’ju rannego vyjavlenija kriticheskih vrozhdennyh porokov serdca». Metodicheskie rekomendacii № 12 / pod red. M.A. Shkol’nikovoj. — M., 2012.
11. Sendelbach D.M., Jackson G.L., Lai S.S. et al. Pulse oximetry screening at 4 hours of age to detect critical congenital heart defects // Pediatrics. — 2008. — Vol. 122, № 4.
12. Reich J.D., Miller S., Brogdon B. et al. The use of pulse oximetry to detect congenital heart disease // J Pediatr. — 2003. — Vol. 142, № 3. — P. 268-272.