L.T. PIMENOV¹, V.V. REMNYAKOV², M.YU. SMETANIN², E.N. AVDEEV², T.E. CHERNYSHOVA¹

 ¹Izhevsk State Medical Academy, Izhevsk

²Republican Clinical and Diagnostic Center of the Ministry of Healthcare of the Udmurt Republic, Izhevsk

 Contact details:

Smetanin M.Yu. — PhD (Medicine), sonographer of the highest category

Address: 87B Lenin St., Izhevsk, Russian Federation, 426009, tel.: +7-912-856-03-33, e-mail: Juvenator1977@yandex.ru

The problem of heart connective tissue dysplasia syndrome is extremely relevant due to the increased risk of rhythm and conduction disorders, infectious endocarditis, thromboembolism and sudden cardiac death (SCD). Structural heart diseases (SHD) are manifestations of minor anomalies of the cardiovascular system development. Dysplastic heart refers to the combination of constitutional, topographical, anatomical, and functional features of the heart in a patient with connective tissue dysplasia (CTD). The standard for the diagnosis of coronary calcification (CC), one of the known predictors of coronary heart disease (CHD) and complications of cardiovascular diseases (CVD), is multispiral computed tomography (MSCT).

The purpose — to identify atherosclerotic lesions of the coronary arteries in young women with undifferentiated connective tissue dysplasia (UCTD) using MSCT.

Material and methods. We examined 35 patients aged 19 to 37 years (the average age was 25.0 ± 6.5 years) with structural heart diseases (SHD), cardialgia of varying severity, with a history of cardiac arrhythmias, shortness of breath with moderate physical exertion. To determine the presence of CC and assess its severity, MSCT with ECG synchronization was performed on a Somatom Sensation computed tomography (Siemens, Germany).

Results. According to the MSCT data, the average value of the Agatston index (calcium index) was 0.14 (0.06) (p < 0.05). The results obtained indicate the absence of coronary calcification (CC) in young women with cardiac manifestations of UCTD.

Conclusion. The assessment of the calcium index using MSCT is a significant tool for predicting the risk of developing CHD and can be used as a screening method in patients with UCTD.

Key words: women, connective tissue dysplasia, structural heart diseases, coronary calcification, multispiral computed tomography, ECG synchronization.

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