D.M. KHAKIMOVA

Kazan State Medical Academy, 36 Butlerova St., Kazan, Russian Federation 420012

Khakimova D.M. — Cand. Med. Sc., Assistant Professor of the Department of Clinical Laboratory Diagnostics, tel. (843) 233-34-84, e-mail: diazkzn@mail.ru

Literature review is focused on contemporary modern methods to detect pre-clinical kidney damage. The main nonimmune mechanisms of progress of chronic kidney disease are the changes in intrarenal hemodynamics. Glomerular hyperfiltration state is considered as one of the first stages of kidney damage.Methods for detection of hyperfiltration include instrumental and laboratory, as well as evaliation formulas and loading tests. The article discusses the mechanisms for development, hyperfiltration identification techniques, comparative analysis and diagnostic significance of these methods are provided.

Key words: glomerular filtration rate, hyperfiltration, loading tests, chronic kidney disease.

 

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