T.M. TIKHONOVA

V.Y. Danylevsky Institute for Endocrine Disorder Research of the National Academy of Medical Sciences of the Ukraine, 10 Artem St., Kharkov, the Ukraine 61002

Tikhonova T.M. — Cand. Med. Sc., senior researcher of the Department of Age-Related Endocrinology, tel. +38057-315-11-88, e-mail: tanya_tykhonova@mail.ru 

The study involved 262 patients with diabetes mellitus (DM), where 121 patients were diagnosed the «slowly progressive autoimmune diabetes in adults», 60 patients — diabetes mellitus of the 1^st type, 81 patients — diabetes mellitus of the 2^nd type. It was determined that despite the similarity of the clinical manifestations of slowly progressive autoimmune diabetes in adults and diabetes mellitus of the 2^nd type, the glycemic level in the definition of the disease in patients with slowly progressive autoimmune diabetes is significantly higher. Growing inefficiency of peroral hypoglycemic therapy in patients with slowly progressive autoimmune diabetes in terms of 2,61±0,15 years from the onset of complaints justifies the feasibility of a timely prescription of the insulin therapy. The prescription of insulin to patients with slowly progressive autoimmune diabetes leads to a significant reduction of carbohydrate metabolism. Therapy witn insulin in patients with slowly progressive autoimmune diabetes is accompanied by also more stable course of the disease and better compensation than in patients with diabetes mellitus of the 1^st type.

Key words: slowly progressive autoimmune diabetes, carbohydrate metabolism.

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