Depression in patients with post-stroke aphasia: diagnosing and clinical features
M.A. KUTLUBAYEV1, A.F. NASRETDINOVA2, L.K. FATKULLINA1, V.A. VOYEVODIN1, L.R. AKHMADEYEVA2
1Republican Clinical Hospital named after G.G. Kuvatov,132 Dostoevsky St., Ufa, Russian Federation 450005
2Bashkir State Medical University, 3 Lenin St., Ufa, Russian Federation 450000
Kutlubayev M.A. — Cand. Med. Sc., staff-neurologist, tel. (347) 228-75-00, e-mail: mansur.kutlubaev@yahoo.com1
Nasretdinova A.F. — resident of the Department of Neurology, Neurosurgery and Medical Genetics, e-mail: omega2005_alia@mail.ru2
Fatkullina L.K. — Speech Pathologist-aphasiology of the Department of Rehabilitation Medicine and Early Neurorehabilitation, tel. (347) 273-46-241
Voyevodin V.A. — Cand. Med. Sc., Head of the Department of Rehabilitation Medicine and Early Neurorehabilitation, tel. (347) 273-46-24, e-mail: vladimir_v@mail.ru1
Akhmadeyeva L.R. — D. Med. Sc., Professor of the Department of Neurology, Neurosurgery and Medical Genetics, tel. (347) 272-56-64, e-mail: la@ufaneuro.org2
We studied psychometric properties of the Russian version of Hospital variant of the 10-component Stroke Aphasic Depression Questionnaire (SADQH-10) in patients with prominent post-stroke speech disorders as well as clinical features of depression in this category of patients. The patients within 1 year after stroke were included. The total of 48 patients were investigated. SADQH-10 showed good psychometric properties (Cronbach-alpha 0,8). Depression was identified in 63% of patients (SADQH-10>6). Symptoms of depression were more prominent in patients with complex motor aphasia, hemorrhagic and recurrent strokes. The severity of depressive symptoms correlated with the degree of limb weakness and speech disorders. SADQH is a perspective tool for diagnosing depression in patients with post-stroke aphasia. The development of depression in stroke survivors with aphasia is associated with severity of both motor and speech deficits.
Key words: stroke, depression, aphasia, diagnosis, clinical features.
REFERENCES
1. Skvortsova V.I., Kontsevoy V.A., Petrova E.A., Savina M.A. Depression and paradepressivnye disorders in cerebral stroke: epidemiology, pathogenesis and risk factors. Zhurnal nevrologii i psikhiatrii, 2009, no. 109, pp. 4-10 (in Russ.).
2. Hackett M.L., Anderson C.S. Predictors of depression after stroke: a systematic review of observational studies. Stroke, 2005, vol. 36, pp. 2296-301.
3. Meader N., Moe-Byrne T., Llewellyn A., Mitchell A.J. Screening for poststroke major depression: a meta-analysis of diagnostic validity studies. J Neurol Neurosurg Psychiatry, 2014, vol. 85, pp. 198-206.
4. Cobley C.S., Thomas S.A., Lincoln N.B., Walker M.F. The assessment of low mood in stroke patients with aphasia: reliability and validity of the 10-item Hospital version of the Stroke Aphasic Depression Questionnaire (SADQH-10). Clin Rehabil., 2012, vol. 26, pp. 372-81.
5. Mead G.E., Hsieh C.-F., Lee R. et al. Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. Cochrane Database of Systematic Reviews 2011, Issue 11. Art. No.:CD009286. DOI: 10.1002/14651858.CD009286.
6. Beaton D.E., Bombardier C., Guillemin F., Ferraz M.B. Guidelines for the process of cross-cultural adaptation of self-report measures. Spine, 2000, vol. 25, pp. 3186-91.
7. Hacker V.L., Stark D., Thomas S. Validation of the stroke aphasic depression questionnaire using the brief assessment schedule depression cards in an acute stroke sample. Br J Clin Psychol., 2010, vol. 49 (Pt 1), pp. 123-7.
8. Cronbach L.J. Coefficient alpha and the internal structure of tests. Psychometrika,1951, vol. 16, pp. 297-334.
9. Orlov A. I. Prikladnaya statistika. Uchebnik [Applied Statistics. Textbook]. Moscow: Ekzamen, 2006. 671 p.
10. Kauhanen M.L., Korpelainen J.T., Hiltunen et al. Aphasia, depression, and non-verbal cognitive impairment in ischaemic stroke. Cerebrovasc Dis., 2000, vol. 10, pp. 455-61.
11. Ramasubbu R. Therapy for prevention of post-stroke depression. Expert Opin Pharmacother., 2011, vol. 12, pp. 2177-87.