S.G. ONUCHIN¹, E.L. ONUCHINA¹, A.O. POZDNAK², O.V. SOLOVEV¹, Yu.S. ONUCHINA

¹Kirov State Medical Academy, 112 Karl Marx St., Kirov, Russian Federation, 610020

²Kazan State Medical Academy, 36 Butlerov St., Kazan, Russian Federation, 420012

³Federal Bureau of Medical and Social Expertise of Ministry of Labour and Social Security of Russia, 3 Ivan Susanin St., Moscow, Russian Federation, 127486

Onuchin S.G. — Cand. Med. Sc., Associate P_rofessor of the Department of Intermediate Level Therapy (Course of Endocrinology), tel. (8332) 56-21-32, e-mail: sgonuchin@rambler.ru

Onuchina E.L. — Cand. Med. Sc., Associate Professor of the Department of Intermediate Level Therapy, tel. (8332) 56-54-26, e-mail: onuchina_07@mail.ru

Pozdnak A.O. — D. Med. Sc., Professor, Head of the Department of therapy and family medicine, tel. (843) 233-34-82, e-mail: ksma@mi.ru

Solovev O.V. — D. Med. Sc., Professor, Head of the Department of Intermediate Level Therapy, tel. (8332) 56-54-26, e-mail: kft@mail.ru

Onuchina Yu.S. — resident physician, tel. +7-909-133-43-48, е-mail: onuchina_07@mail.ru

There was evaluated the efficacy of sulodexide in the complex therapy in patients (n=65) with type 2 diabetes with diabetic foot syndrome and diabetic nephropathy. The period of active therapy was 1 year; 3 years later there were estimated the long-term results of therapy. It was found that in the use of sulodexide in a correctly integrated part of antidiabetic, hypolipidemic, antihypertensive therapy it is possible to achieve not only target conventional indicators, but also effective nephroprotection. The article indicates improving renal function, decreasing endothelial dysfunction and ultimately faster healing of ulcers, prevention of amputation of the lower limbs, reduction of cardiovascular events with securing a favorable outcome in the follow-up.

Key words: diabetic foot syndrome, diabetic nephropathy, sulodexide.

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