E.V. AGAPHONOVA^1,2, I.D. RESHETNIKOVA¹

¹Kazan Scientific and Research Institute of Epidemiology and Microbiology of Rospotrebnadzor, 67 B. Krasnaya Str., Kazan, Russian Federation, 420015

²Kazan State Medical University, 49 Butlerov Str., Kazan, Russian Federation, 420012

Agaphonova E.V. ― Cand. Med. Sc., Head of clinical and diagnostic laboratory, Assistant of the Department of propaedeutics of children’s diseases and faculty pediatrics with a course of children’s diseases of medical faculty, tel. (843) 236-55-87, e-mail: Agafono@mail.ru

Reshetnikova I.D. ― Cand. Med. Sc., Associate Professor, Deputy Director on scientific and medical work, tel. (843) 236-67-21, e-mail: reshira@mail.ru

The article combines the results of researches on the use of the component diagnostics of allergic diseases in children. Characteristics of major and minor components of allergens (food, pollen, household, epidermal) is presented. Problems of cross-reactivity, risk assessment of systemic and local reactions, optimization of diagnosing food sensitization and predicting the efficacy of allergen immunotherapy are discussed. The high practical and scientific significance of component technology in the diagnostics of Ig E diseases in children is demonstrated.

Key words: allergic diseases, components of allergens, children, diagnostics.

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