Sh.M. ISMAGILOV, M.N. GILYALOV, M.F. ISMAGILOV

Kazan State Medical University, 49 Butlerov Str., Kazan, Russian Federation, 420012

Ismagilov Sh.M. ― Cand. Med. Sc., Associate Professor of the Otorhinolaryngology Department, tel. +7-917-391-18-03, e-mail: ism_sh63@mail.ru

Gilyalov M.N. ― postgraduate student of the Otorhinolaryngology Department, tel. +7-917-221-51-34, e-mail: gilyalov_m@mail.ru

Ismagilov M.F. ― D. Med. Sc., Professor of the Department of Neurology, Neurosurgery and Medical Genetics, tel. +7-937-256-80-18, e-mail: ism_sh63@mail.ru

The article presents the results of the study showing that the inflammation in the nasal cavity and paranasal sinuses affects the functional state of the mucous membrane, inhibiting the respiratory and transport function of the nose, accompanied by a disturbance of homeostasis in the form of slight acidosis, which can be better corrected by the treatment, including the impact on vegetotropic effect on the body. Thus, taking into account the vagotonic functioning of vegetative nervous system in patients with rhinosinusitis, it is necessary to affect the pathogenesis of the disease using simpatotropic therapy.

Key words: rhinosinusitis, the state of the vegetative nervous system, simpatotropic therapy, Dimephosphon.

REFERENCES

1. Ivanchenko O.A., Lopatin A.S. Chronic rhinosinusitis: epidemiology, classification, etiology, pathogenesis. The modern view on the problem. Vestn. otorinolar, 2012, no. 2, pp. 91-96 (in Russ.).
2. Lopatin A.S., Svistushkin V.M. Ostryy rinosinusit: etiologiya, patogenez, diagnostika i printsipy lecheniya. Klinicheskie rekomendatsii [Acute rhinosinusitis: etiology, pathogenesis, diagnosis and treatment principles. Clinical guidelines]. Moscow: Rossiyskoe Obshchestvo rinologov, 2008. 28 p.
3. Topolyanskiy V.D., Strukovskaya M.V. Psikhosomaticheskie rasstroystva [Psychosomatic disorders], Moscow: Meditsina, 1986. 256 p.
4. Ishino T. Establishment of osteoblast culture from human etmoidal sinus. Auris Nasus Larynx, 2003, vol. 30, no. 1, pp. 45-51.
5. Batrak M.V., Borzov E.V., Safronov B.G. Heart rate variability in patients before and after surgery in the nasal cavity. Ros. otorinolar, 2009, no. 6 (43), pp. 19-23 (in Russ.).
6. Ismagilov Sh.M., Gilyalov M.N. The prevalence of type vegetative response Kazan population. Ros. rinol, 2014, no. 2, p. 15 (in Russ.).
7. Ismagilov M.F., Galiullin A.N., Ismagilov Sh.M. et al. Prevalence of diseases in the pedigrees of healthy individuals in different types of autonomic constitution. Fundamental’nye issledovaniya, 2014, vol. 5, no. 10, pp. 878-881 (in Russ.).
8. Vegetativnye rasstroystva: klinika, diagnostika, lechenie, pod red. A.M. Veyna [Autonomic dysfunction: clinical features, diagnosis, treatment. Ed. by A.M. Veyn]. Moscow: OOO “Meditsinskoe informatsionnoe agentstvo”, 2003. 752 p.
9. Ismagilov M.F., Alevetdinov R.I., Studentsova I.A. O rezul’tatakh primeneniya dimefosfona v klinike nervnykh bolezney vegetativno-sosudistykh disfunktsiy u detey. Otchet dlya farmokomiteta MZ SSSR “DSP” [On the results of application dimefosfona in the clinic of nervous diseases vegetative-vascular dysfunction in children. Report to the Ministry of Health of the USSR farmokomiteta “DSP”]. Kazan, 1983.