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  • Comparison of the results of transvaginal of cervix uterine with the level of biochemical markers in case of prenatal screening of the first trimester in FMF module

    Редакция | 2014, Articles based on dissertstions, Practical medicine 03 (14) Modern questions of diagnostics | 15 июля, 2014

    K.V. YANAKOVA1, L.E. TEREGULOVA2,3, Z.I. VAFINA2, M.G. TUKHBATULLIN3

    1Municipal Clinical Hospital № 7, 54 Marshala Chuykova St., Kazan, Russian Federation 420136

    2Republican Clinical Hospital of Ministry of Health of the Republic of Tatarstan, 138 Orenburgskiy Trakt St., Kazan, Russian Federation 420064

    3Kazan State Medical Academy, 36 Butlerova St., Kazan, Russian Federation 420012

    Yanakova K.V. — postgraduate student of the department of ultrasound diagnosis,tel. +7-905-377-11-69, e-mail: xristinaki_80@hotmail.com1

    Teregulova L.E. —Candidate of Medical Science,Head of the division of ultrasound investigation, assistant professor of the department of ultrasound diagnosis, tel. (843) 264-54-14, e-mail: tereg1@mail.ru2,3

    Vafina Z.I. —Head of medicogenetic center, tel. +7-917-265-82-20, e-mail: vzulfia@mail.ru2

    Tukhbatullin M.G. —D.Med.Sc., Professor, Head of the department of ultrasound diagnosis, tel. +7-900-326-20-03, e-mail: Munir.Tuhbatullin@tatar.ru3

    The article presents the results of ultrasound investigation of the cervix uteri of 100 pregnant women at 11-13,6 weeks of pregnancy. Measurement of the cervix uteri was made by standards recommended by the Fetal Medicine Foundation. In the framework of a combined screening of the first trimester was defined the level of biochemical markers of chromosomal abnormalities: β-hCG (chorionic gonadotropin), PAPP-A (pregnancy-associated plasma protein-A). Were obtained data of direct correlation of length of the cervix and the level of PAPP-A (pregnancy-associated plasma protein-A), as well as of no correlation with the level of β-hCG.

    Key words: combined screening of the first trimester, cervix uteri, biochemical markers of chromosomal abnormalities, β-hCG (chorionic gonadotropin), PAPP-A (pregnancy-associated plasma protein-A).

     

    REFERENCES

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    6. Teregulova L.E., Vafina Z.I., Abuseva A.V. et al. Analysis of the results of mass centralized prenatal screening I trimester of pregnancy in the Republic of Tatarstan for 2012. Prakticheskaya meditsina, 2013, vol. 2, no. 1, 2, pp. 150-155 (in Russ.).

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    12. Celik E., To A.M., Gajewska K. et al.Fetal Medicine Foundation Second Trimester Screening Group. Cervical length and obstetric history predict spontaneous preterm birth: development and validation of a model to provide individualized risk assessment. Ultrasound Obstet. Gynecol., 2008, vol. 31, pp. 549-54.

    13. Souka A.P., Papastefanou I., Michalitsi V.et al.A predictive model of short cervix at 20-24 weeks using first-trimester cervical length measurement and maternal history. Prenat. Diagn., 2011, vol. 31, pp. 202-206.

    14. Greco E., Gupta R., Syngelaki A. et al. First trimester screening for spontaneous preterm delivery with maternal characteristics and cervical length. Fetal Diagn. Ther., 2012, vol. 31, pp. 154-161.

    Метки: biochemical markers of chromosomal abnormalities, cervix uteri, combined screening of the first trimester, K.V. YANAKOVA, L.E. TEREGULOVA, M.G. TUKHBATULLIN, PAPP-A (pregnancy-associated plasma protein-A), Z.I. VAFINA, β-hCG (chorionic gonadotropin)

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