G. L. IGNATOVA, O.V. RODIONOVA, I.A. ZAKHAROVA, E.A. ALEKSANDROVA
South-Ural State Medical University, Chelyabinsk
Regional Clinical Hospital № 4, Chelyabinsk

Ignatova Galina Lvovna
Doctor of Medical Science, Head of the Department of therapy of the faculty of postgraduate and professional additional education
65-81 Lenina Ave., Chelyabinsk 454092
tel. (351) 742-66-40, e-mail: iglign@mail.ru

The article presents the study results of 31 young patients with bronchial asthma. The characteristics of clinical and functional features of these patients is given. It was revealed that the presence of bronchial asthma of mild to moderate severity is not accompanied by changes in lung function, whereas during the body plethysmography there was founded an increase in pulmonary residual volume. These findings indicate the need for а depth examination of patients with asthma, particularly, with body plethysmography.   

Key words: Bronchial asthma, young patients, remodelling of bronchus, body plethysmography.

REFERENCES

1. Knjazheskaja N.P. Terapija Simbikortom Turbuhalerom v rezhime edinogo ingaljatora (SMART): aktual’nye voprosy i ih reshenija // Atmosfera. Pul’monologija i allergologija. — 2012. — № 4. — S. 19-22.

2. Masoli M., Fabian D., Holt S., Beasley R. The global burden of asthma: executive summary of the GINA Dissemination Committee report // Allergy. — 2004. — 59 (5). — P. 469-78.

3. Fedosenko S.V., Shmelev E.I. Jeffektivnost’ i bezopasnost’ preparata Tevakomb v lechenii bol’nyh bronhial’noj astmoj s pozicii dokazatel’noj mediciny // Pul’monologija i allergologija. — 2012. — № 2. — S. 19-22.

4. GINA Report, Global Strategy for Asthma Management and Prevention. Update 2011 // http://www.ginasthma.org

5. Fuhlbrigge A.L. et al. Mild intermittent asthma: CT assessment of bronchial crocc-sectional area and lung attenuation at cjntrolled lung volume// Am. J. Respir. Crit. Care Med. — 2002. — Vol. 166. — 1044 p.

6. Chikina S.Ju. Novyj vzgljad na fenotipy bronhial’noj astmy (obzor literatury) // Atmosfera. Pul’monologija i allergologija. — 2012. — № 2. — S. 2-6.

7. Hyde D.M. et al. Lung penetration and patient adherence considerations in the management of asthma// J. Allergy Clin. Immunol. — 2009. — Vol. 124. — P. S72.

8. Battaglia S, den Hertog H., Timmers M.C. et al. Small airways function and molecular markers in axhaled air in mild asthma // Thorax. — 2005. — Vol. 60. — P. 639-644.

9. Sinopal’nikov A.I., Belocerkoveckaja Ju.G. Kak uluchshit’ kontrol’ nad bronhial’noj astmoj bez uvelichenija ob#ema bazisnoj terapii? // Pul’monologija. — 2013. — № 1. — S. 77-84.

10. Chernjak A.V. Funkcional’nye metody diagnostiki patologii melkih dyhatel’nyh putej // Atmosfera. Pul’monologija i allergologija. —2013. — № 1. — S. 36-41.

11. Kraft M. et al // Am. J. Respir. Crit. Care Med. — 2001. — Vol. 163. — 1551 p.