A.R. RAKHMATULLIN, Yu.Z. KARIPOVA, V.Ph. TUNIK, O.V. ZAPLAKHOVA, E.V. IVANOVA, K.Z. BAKHTIYAROVA

Bashkir State Medical University, 3 Lenina St., Ufa, Russian Federation, 450000

Rakhmatullin A.R. — postgraduate student of the Department of Neurology with courses of Neurosurgery and Medical Genetics, tel. (3472) 48-28-01, e-mail: airatraxmatullin@rambler.ru

Karipova Yu.Z. — resident physician of the Department of Neurology with courses of Neurosurgery and Medical Genetics, tel. (3472) 48-28-01, e-mail: napolittano@mail.ru

Tunik V.F. — Associate Professor of the Department of Neurology with courses of Neurosurgery and Medical Genetics, Head of the Neurological Department of the Republican Clinical Hospital, tel. (3472) 48-28-01, email: vtunik@yandex.ru

Zaplakhova O.V. — neurologist of the Republican Center of multiple sclerosis, e-mail: fim72@mail.ru

Ivanova E.V. — postgraduate student of the Department of Neurology with courses of Neurosurgery and Medical Genetics, tel. (3472) 48-28-01, e-mail: www.elena-ufa@yandex.ru

Bakhtiyarova K.Z. — Professor of the Department of Neurology with courses of Neurosurgery and Medical Genetics, tel. (3472) 48-28-01, e-mail: bsmu-neuro@yandex.ru

In this article is presented a clinical observation of a patient with multiple sclerosis and autoimmune thrombocytopenic purpura, confirming the similarity of the pathogenesis of two autoimmune diseases.

Key words: multiple sclerosis, autoimmune thrombocytopenic purpura, autoimmune thrombocytopenia. 

REFERENCES

1. Alemany-Rodríguez M.J., AladroY., Amela-Peris R. et al. Autoimmune diseases and multiple sclerosis. Revista de Neurol, 2005, May, vol. 16-31, 40(10), pp. 594-7.
2. Sultanova I.V., Kolikova Yu.O., Ishmukhametova D.G. et al. Clinical and immunological features of diffuse connective tissue disease in patients with multiple sclerosis. Nevrologicheskiy vestnik, 2003, vol. XXXV, iss. 1-2, pp. 18-21 (in Russ.).
3. Alan Dzh. Tompson, Kris Polman, Raynkhard Kholfel’d. Rasseyannyy skleroz. Klinicheskie aspekty i spornye voprosy [Multiple sclerosis. Clinical aspects and issues], 2001. 424 p.
4. Fatkullina U.Sh., Zaynullina L.F., Bakhtiyarova K.Z., Vakhitova Yu.V. NMDA-receptor T cells regulate the synthesis of cytokines in patients with multiple sclerosis. Immunologiya, 2013, vol. 34, no. 6, pp. 339-343 (in Russ.).
5. Hideaki Matsui, Fukashi Udaka, Akiko Tamura et al. Multiple sclerosis following splenectomy as a treatment for idiopathic thrombocytopenic purpura. Internal Medicine, 2005, vol. 44, no.7, pp. 35-37.
6. Yokote H., Nagasawa M., Ichijo M. et al. Autoimmune polyendocrine syndrome-3 in a patient with late-onset multiple sclerosis. Neurologist, 2012, Mar., vol. 18(2), pp. 83-84.
7. Deretzi G., Kountouras J., Zavos C. et al. Multiple sclerosis, idiopathic dilated cardiomyopathy, and insulin-dependent diabetes mellitus: a common mechanism of irregular immune regulation. Neurologist, 2011, May, vol. 17(3), pp. 172-175.
8. Mikulkova Z., Praksova P., Stourac P. et al. Numerical defects in CD8+CD28 – T-suppressor lymphocyte population in patients with type 1 diabetes mellitusand multiple sclerosis. Cell Immunol, 2010, vol. 262(2), pp. 75-79.
9. Vorob’ev A.I. Rukovodstvo po gematologii [Guide to Hematology], 2005. Vol. 3, 409 p.
10. Baydina T.V., Akintseva Yu.V., Trushnikova T.N. Platelet serotonin in multiple sclerosis and its relation with fatigue syndrome. Neyrokhimiya, 2013, vol. 30, no. 3, pp. 254 (in Russ.).