E.G. MENDELEVICH, R.G. KOKURKINA

Kazan State Medical University, Kazan

Contact details:

Mendelevich E.G, MD, Professor of the Neurology and Rehabilitation Department

Address: 49 Butlerov St., Russian Federation, Kazan, 420012, tel.: +7-987-296-15-16, e-mail: emendel@mail.ru

This paper presents literature review on cognitive impairments in patients with CM1, data on which began to be formed in the recent years. Data on the predominant deficit in the structure of executive functioning in patients with CM1 are presented. The genesis of cognitive deficits in patients with CM1 is most often considered in the context of cerebellar dysfunction and damage to the connections of the cerebellum with the prefrontal cortex, which leads to dysmetria of thinking and emotions. Data from other studies are presented that consider the role of additional factors of cognitive dysfunction in CM1, such as pain and emotional disorders.

Key words: Chiari malformation, cognitive-affective syndrome, executive functions, «dysmetria of thinking».

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