L.V. VASILYEVA¹, A.A. KOLYAGIN², E.YU. SUSLOVA¹, E.V. GOSTEVA¹

¹Voronezh State Medical University named after N.N. Burdenko, Voronezh

²Voronezh City Clinical Hospital No. 20, Voronezh

  Contact details:

Suslova E.Yu. — PhD (Medicine), Associate Professor, Department of Propaedeutics of Internal Diseases

Address: 10 Studencheskaya St., 394036 Voronezh, Russian Federation, tеl.: +7-951-567-02-12, e-mail: suslova_ekaterina2502@mail.ru

The purpose was to evaluate the structure of the comorbid background and geriatric status in patients with osteoarthritis (OA) of the lower extremities and chronic kidney disease (CKD) at the outpatient stage.

Material and methods. We examined 284 patients (108 men and 176 women) aged 65–89 years, of whom 128 (45%) were elderly and 156 (55%) were senile. The OA and CKD diagnoses were verified according to the relevant clinical recommendations; senile asthenia (SA) was verified by the «Age is not a hindrance» scale.

Results. High polymorbidity was noted (91.5% had ≥3 diseases), as well as the risk of polypragmasia (median — 7 drugs). The prevalence of geriatric syndromes was 82.7%, with a significant predominance in old age — the differences were noted for SA (48.1%), movement disorders (52.9%) and sensory deficits (44.3%). The strongest association with age was found for sensory deficits (r = 0.77), movement disorders (r = 0.72) and SA (r = 0.71) (p < 0.001). A high correlation was found between the number of drugs and the presence of ≥3 syndromes (r = 0.72; p < 0.001), between SA and hypertension (r = 0.67; p < 0.001). SA correlated with osteoporosis (r = 0.59) and comorbidity (r = 0.64). BMI and waist circumference were moderately associated with movement disorders (r = 0.47; p < 0.01). An increased likelihood of senile asthenia in the study cohort was noted from the age of 77.0 years (according to ROC analysis).

Conclusion. The following categories must be screened for SA at the outpatient stage: senile persons, patients with polymorbidity of geriatric syndromes (≥3) and polypragmasia.

Key words: geriatric syndromes, comorbidity, osteoarthritis, outpatient patients

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