L.I. BAGAUTDINOVA, D.S. SARKSYAN, M.V. DUDAREV, O.V. MALININ, G.K. KUSTARNIKOV, V.I. SHAKHOV, I.E. MALININ

Izhevsk State Medical Academy

Bagautdinova Lilia Ismagilovna

Graduate student of the Department of polyclinic therapy with courses of Clinical Pharmacology and Preventive Medicine of Advanced Training Faculty and outpatient pediatrics
43-45 Saburova Str., Izhevsk 426068
tel. 8-912-455-84-60, e-mail: halitova-lilya@rambler.ru

The purpose of the study the clinical picture of a «new» infection ― ixodic Lyme borreliosis caused by B. miyamotoi. The work is based on the results of a prospective observation of 76 patients with disease caused by B. miyamotoi. Diagnosis is confirmed by PCR. The study shows that a syndrome of fever and a manifestation of intoxication ― headache, fatigue, myalgia, vomiting and other substances are at the heart of a typical clinical picture. In some cases, for unclear reasons, the pathological process involves internal organs ― lungs, liver, kidney, gastrointestinal tract, heart. This fact may be the cause of a diagnostic error.

Key words: ixodic Lyme borreliosis, Borrelia miyamotoi, clinical picture,Udmurtia. 

REFERENCES

1. Anguita J., Hedrick M.N., Fikrig E. // Fems. Microbiol. Rew. ― 2003. ― Vol. 27. ― P. 493-504.

2. Anguita J., Samanta S., Revilla B. et al. // Infect. Immunol. ― 2000. ― Vol. 68. ― P. 1222-1230.

3. Liang F.T., Nelson F.K., Fikrig E. // J. Exp. Med. ― 2002. ― Vol. 196. ― P. 275-280.

4. Lyme Borreliosis and Tick-Borne Encephalitis / Eds. Oschmann P., Kraiczy P. et al. ― Bremen, 1999, Germany. ― 144 p.

5. Nadelman R.B.,Wormser G.P. Lyme borreliosis // Lancet. ― 1998. ―– Vol. 352. ― P. 557-565.

6. Fukunaga M., Takahashi Y., Tsuruta Y. et al. Genetic and phenotypic analysis of Borrelia miyamotoi sp. nov., isolated from the ixodid tick Ixodes persulcatus, the vector for Lyme disease in Japan // Int. J. Syst. Bacteriol. ― 1995. ― 45. ― P. 804-810.

7. Platonov A.E., Karan’ L.S., Koljasnikova N.M. i dr. Taksonomicheskaja pozicija i geneticheskoe raznoobrazie vida borrelij Borrelia miyamotoi ― vozbuditelja «novogo» iksodovogo kleshhevogo borrelioza. V / Pokrovskij V.I. (red) // Molekuljarnaja diagnostika ― 2010. ― T. 2. ― M: Kiseleva N.V., 2010. ― S. 250-256.

8. Kapan’ L.S., Rudnikova N.A., Bulgakova T.A. i dr. PCR-diagnostika klinicheskih sluchaev borreliozov i rikketsiozov V / Pokrovskij V.I. (red).// Genodiagnostika infekcionnyh zabolevanij. ― T. 2. ― M.: Medicina dlja vseh, 2004. ― S. 35-37.

9. Platonov A.E., Karan’ L.S., Garanina S.B. i dr. Prirodno-ochagovye infekcii v XXI veke v Rossii // Jepidemiol. i infekc. bol. ― 2009. ― 2. ― S. 38-44.

10.Platonov A.E., Maleev V.V., Karan’ L.S. Borrelioznye vozvratnye lihoradki: zabytye i novye // Ter. Arhiv. ― 2010. ― 11. ― S. 74-80.

11.Platonov A.E., Karan L.S., Kolyasnikova N.M. et al. Humans infected with the relapsing fever spirochete Borrelia miyamotoi, Russia // Emerg. Infect. Dis. ― 2011. ― 17 (10). ― S. 1816-1822.