G.I. NURULLINA¹, T.N. KHALFINA¹, O.YU. FAKHRUTDINOVA², L.A. GAINUTDINOVA¹, R.D. MUTIGULLIN¹

 ¹Kazan State Medical University, Kazan

²Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan, Kazan

 Contact details:

Nurullina G.I. — PhD (medicine), Associate Professor of the Department of Hospital Therapy

Address: 49 Butlerov St., Kazan, Russian Federation, 420012, tel.: +7 (843) 290-18-20, e-mail: nurguzel@yandex.ru

 The article presents the results of a clinical observation of a case of acute kidney injury with an end-stage renal disease development in a patient who had had COVID-19 twice. The difficulties of the diagnostic search and further therapy are described. The characteristics of the clinical course and functional features of the patient are given. The mechanisms of the SARS-CoV-2 virus impact on the human body and their role in kidney damage are considered. This clinical case is an example of a rapid loss of kidney function with the development of end-stage renal disease against the background of COVID-19.

Key words: new coronavirus infection, acute kidney injury, chronic kidney disease.

REFERENCES

1. Vremennye metodicheskie rekomendatsii Minzdrava Rossii “Profilaktika, diagnostika i lechenie novoy koronavirusnoy infektsii (COVID-19)” [Temporary guidelines of the Ministry of Health of Russia «Prevention, diagnosis and treatment of a new coronavirus infection (COVID-19)»]. Moscow, 2022.
2. Schaubroeck H., Vandenberghe W., Boer W. et al. Acute kidney injury in critical COVID-19: a multicenter cohort analysis in seven large hospitals in Belgium. Crit Care, 2022, Jul 25, vol. 26 (1), p. 225. DOI: 10.1186/s13054-022-04086-x PMID: 35879765; PMCID: PMC9310674.
3. Hultström M., Lipcsey M., Wallin E. et al. Severe acute kidney injury associated with progression of chronic kidney disease after critical COVID-19. Crit Care, 2021, vol. 25(1), p. 37. Published 2021 Jan 25. DOI: 10.1186/s13054-021-03461-4
4. Chauhan A.J., Wiffen L.J., Brown T.P. COVID-19: A collision of complement, coagulation and inflammatory pathways. J Thromb Haemost., 2020, Sep., vol. 8 (9), pp. 2110–2117. DOI: 10.1111/jth.14981 Epub 2020 Aug 27. PMID: 32608159; PMCID: PMC7361520.
5. Long J.D., Strohbehn I., Sawtell R. et al. COVID-19 Survival and its impact on chronic kidney disease. Transl Res., 2022, vol. 241, pp. 70–82. DOI: 10.1016/j.trsl.2021.11.003