O.S. KHAYRUTDINOVA¹, E.I. BOGDANOV¹

 ¹Kazan State Medical University, Kazan

 Contact details:

Khayrutdinova O.S. — Assistant Lecturer of the Department of Neurology and Rehabilitation

Address: 49 Butlerov St., Kazan, Russian Federation, 420012, tel.: +7-962-562-44-27, e-mail: khayrutdinova.os@gmail.com

 The article considers the relation between clinical manifestations of central sensitization (CS) and the course of episodic migraine as an independent nosology and combined with cervicalgia or cervicogenic headache. The research objective was to study the comorbid pathologies in patients with episodic migraine, characteristic for central sensitization — anxiety, depression, cervicalgia, cervicogenic headache, and sleep disorders. We found the relationship between the intensity of migraine pain syndrome, migraine duration in anamnesis, and the central sensitization index — CSI. At the same time, the CS intensity also directly depended on the number of involved muscles and triggers. The effect was shown of the cervicogenic factor as a predictor or trigger in patients with migraine and cervicogenic headache, as well as the significant impact of clinical manifestations of CS on the quality of life of patients with episodic migraine.

Key words: episodic migraine, central sensitization, cervicogenic headache. cervicolgia.

REFERENCES

1. Woolf C. Central sensitization: Implications for the diagnosis and treatment of pain. Pain, 2011, vol. 152 (suppl), pp. 2–15. DOI: 10.1016/j.pain.2010.09.030
2. Suzuki K., Suzuki S., Shiina T., Kobayashi S., Hirata K. Central Sensitization in Migraine: A Narrative Review. J Pain Res, 2022, vol. 15, pp. 2673–2682. DOI: 10.2147/JPR.S329280
3. IASP Terminology. IASP, 2019, available at: https://www.iasp-pain.org/terminology?navItemNumber=576#Centralsensitization
4. Nijs J., Torres-Cueco R., van Wilgen C.P. et al. Applying modern pain neuroscience in clinical practice: criteria for the classification of central sensitization pain. Pain Physician, 2014, vol. 17 (5), rr. 447–457. DOI: 10.36076/ppj.2014/17/447
5. Ashina M., Katsarava Z., Do T.P. et al. Migraine: epidemiology and systems of care. Lancet, 2021, vol. 397, pp. 1485–1495. DOI: 10.1016/S0140-6736(20)32160-7
6. Latysheva N.V. Comorbid diseases in patients with chronic migraine. Avtoreferat. Moscow, 2020. Pp. 4–5, 113–122 (in Russ.).
7. Lampl C. et al. Neck pain in episodic migraine: premonitory symptom or part of the attack? J Headache Pain, 2015, vol. 16, p. 566. DOI: 10.1186/s10194-015-0566-9
8. Headache Classification Committee of the International Headache Society (IHS). The international classification of headache disorders, 3rd edition. Cephalalgia, 2018, vol. 38 (1), pp. 1–211. DOI: 10.1177/0333102417738202
9. Sjaastad O., Bovim G. Cervicogenic headache. The differentiation from common migraine. An overview. Funct Neurol, 1991, vol. 6 (2), rr. 93–100. PMID: 1916461