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  • Clinical manifestations and patient-specificTreatment regimen of cytomegalovirus hepatitis in infants

    Редактор | 2014, Articles based on dissertstions, Practical medicine 02 (14) Neurology. Psychiatry | 22 апреля, 2014

    R.A. USHAKOVA, O.P. KOVTUN

    Ural State Medical University, 3 Repina St., Ekaterinburg, Russian Federation, 620219

    Ushakova R.A. — Candidate of Medical Sciences, Associate Professor of the Department of Pediatrics and Neonatology, tel. +7-912-667-48-81, e-mail: rima.ushakova@mail.ru

    Kovtun O.P. — Doctor of Medical Sciences, Professor, Head of the Department of Pediatrics and Neonatology, tel. (343)214-86-79, e-mail: kovtun@usma.ru 

    43 first life year children with CMV-hepatitis were observed. The features of CMV-hepatitis include prolonged jaundice, cholestasis, early onset of the disease with the increase of transaminase level. The hepatolienal syndrome is combined with lymphadenectasia, enterocolitis, perinatal lesion of CNS, myatony and hydrocephalic syndrome, pyramidal insufficiency. The personified complex program of CMV-hepatitis treatment in 37 patients allowed to achieve normalization of transaminase and alkaline phosphatase levels, liver and spleen sizes reduced.

    Key words: children, cytomegalovirus hepatitis, antiviral therapy.

     

     

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    Метки: antiviral therapy, Children, cytomegalovirus hepatitis, O.P. KOVTUN, Practical medicine 02 (14) Neurology. Psychiatry, R.A. USHAKOVA

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