Clinical-laboratory characteristic of hemorrhagic fever with renal syndrome in adults and children
A.KH. BULATOVA1, 3, I.M. KHAERTYNOVA1, V.G. SHAKIROVA1, KH.S. KHAERTYNOV2, Z.L. KHAMIDULLINA3, L.V. POLADOVA4
1Kazan State Medical Academy — Branch Campus of the FSBEI FPE RMACPE MOH Russia, Kazan
2Kazan State Medical University, Kazan
3Republic Clinical Infectious Hospital named after Prof. A.F. Agafonov, Kazan
4Children’s Republic Clinical Hospital, Kazan
Contact details:
Bulatova A.Kh. — post-graduate student of the Department of Infectious Diseases
Address: 36 Butlerov St., Kazan, Russian Federation, 420012, tel.: +7-909-308-12-51, e-mail: Asiyakhaertynova@gmail.com
The article presents the results of a comparative analysis of clinical and laboratory parameters of hemorrhagic fever with renal syndrome (HFRS) in adults and children in 2019–2022. HFRS is predominantly registered among the adult population, children account for only about 2%. Features of HFRS clinical and laboratory parameters in children are few and contradictory. Therefore, it is of particular interest to study the peculiarities of the HFRS course in children and to compare them with the course of this infection in adults.
Key words: hemorrhagic fever, acute kidney injury, children.
REFERENCES
- Savitskaya T.A., Ivanova A.V., Isaeva G.Sh. et al. Evaluation of the epidemiological situation of hemorrhagic fever with renal syndrome in the world and Russia, forecast for 2020. Problemy osobo opasnykh infektsiy, 2020, no. 2, pp. 62–70 (in Russ.).
- Ivanova A.V., Popov N.V., Karnaukhov I.G., Chumachkova E.A. Hantavirus diseases: a review of the epidemiological situation and epidemiological risks in the regions of the world. Problemy osobo opasnykh infektsiiy, 2021, no. 1, pp. 23–31 (in Russ.).
- Daviduk Y.N., Kabwe E., Shakirova V.G. et al. Characterization of the Puumalaorthohantavirus Strains in the Northwestern Region of the Republic of Tatarstan in Relation to the Clinical Manifestations in Hemorrhagic Fever With Renal Syndrome Patients. Frontiers in Pharmacology, 2019, vol. 10, pp. 1–9.
- Dzagurova T.K., Tkachenko E.A., Ishmukhametov A.A., Balovneva M.V. et al. Severe hantavirus disease in children. Journal of Clinical Virology, 2018, vol. 101, pp. 66–68.
- Tariq M., Kim D. Hemorrhagic Fever with Renal Syndrome: Literature Review, Epidemiology, Clinical Picture and Pathogenesis. Infection and Chemotherapy, 2022, vol. 54 (1), pp. 1–19.
- Shakirova V.G., Gayfullina E.G., Khaertynova I.M. Hemorrhagic fever with renal syndrome: analysis of the epidemiological situation in the Republic of Tatarstan for the period 2003–2015. Dnevnik Kazanskoy meditsinskoy shkoly, 2017, no. 2 (16), pp. 21–24 (in Russ.).
- Huttunen N., Mäkelä S., Pokka T. et al. Systematic literature review of symptoms, signs and severity of serologically confirmed nephropathia epidemica in paediatric and adult patients. Scandinavian Journal of Infectious Diseases, 2011, vol. 43 (6–7), pp. 405–410.
- Pozdeeva O.S., Mokhova O.G., Kankasova M.N. et al. Hemorrhagic fever with renal syndrome in children. Prakticheskaya meditsina, 2016, no. 8, pp. 53–57 (in Russ.).
- Egorov V.B., Valishin D.A., Ushakova I.A., Svirina A.S. Features of clinical manifestations of hemorrhagic fever with renal syndrome in children and adolescents. Prakticheskaya meditsina, 2012, no. 7 (62), pp. 131–136 (in Russ.).
- Echterdiek F., Kitterer D. et al. Clinical course of hantavirus-induced nephropathiaepidemica in children compared to adults in Germany — analysis of 317 patients. Pediatric Nephrology, 2019, vol. 34 (7), pp. 1247–1252.
- Peco-Antić A., Popović-Rolović M., Popović D. et al. Hemorrhagic fever with renal syndrome in children. Srp Arh Celok Lek, 1991, vol. 119 (1–2), pp. 58–61.
- Zhang L., Ma Qs., Zhang Y. et al. Analysis of misdiagnosed cases of hemorrhagic fever with renal syndrome in children: two cases and literature review. BMC Nephrology, 2019, vol. 20 (1), r. 383.
- Enikeeva Z.M., Akhmadeeva E.N., Agzamova R.F. Clinical course of complications of hemorrhagic fever with renal syndrome in children. Meditsinskiy vestnik Yuga Rossii, 2013, no. 2, pp. 60–64 (in Russ.).
- Pavlov V.N., Kazikhinurov A.A., Safiullin R.I. et al. Abdominal syndrome in patients with severe hemorrhagic fever and acute renal failure. Meditsinskiy vestnik Bashkortostana, 2015, no. 3, pp. 106–108 (in Russ.).
- Dzagurova T.K., Ishmukhametov A.A., Bakhtina V.A. et al. Analysis of a group outbreak of hemorrhagic fever with renal syndrome caused by the Sochi virus. Voprosy virusologii, 2019, no. 64 (1), pp. 36–41 (in Russ.).