Clinical course and outcomes of rapid and precipitated labor in women
M.E. ZHELEZOVA¹, L.I. MALTSEVA¹, T.P. ZEPHIROVA¹, D.E. TSYPLAKOV²
Kazan State Medical Academy, 51 Bolshaya Krasnaya St., Kazan, Russian Federation 420015
Kazan State Medical University, 49 Butlerova St., Kazan, Russian Federation 420012
Zhelezova M.E. — Candidate of Medical Science, associate professor of the department of obstetrics and gynecology № 1, tel.: (843) 236-45-11, +7-919-627-13-66. e-mail: gelezovam@gmail.com¹
Maltseva L.I. — D. med. Sc., Professor, Head of the department of obstetrics and gynecology № 1, tel. +7-905-314-40-51, e-mail: laramalc@mail.ru¹
Zephirova T.P. — D. med. Sc., Professor of the department of obstetrics and gynecology № 1, tel. +7-987-290-45-99,e-mail: tzefirova@gmail.com¹
Tsyplakov D.E. — D. med. Sc., Professor, Head of the Department of pathological anatomy, tel. +7-919-723-14-48, e-mail:
In the article pregnancy course and outcomes of rapid and precipitated labor in 115 women with full-term duration of gestation are analyzed. It was found that in 73% of cases act of delivery was accompanied by various maternal and perinatal complications, where soft injuries to birth canal of a mother, partial premature detachment of normally localized placenta, intrauterine hypoxia dominated. Complications of early neonatal period were observed in 95% of newborns. In a majority of cases rapid and precipitous labor are subject not to alvus hyperactivity but to lowered resistance of cervix uteri. Morphological and immunohistochemical analyses of the cervix uteri in women with rapid and precipitated labor were done.
Key words: rapid and precipitated labor, maternal complications, perinatal complications, morphological analysis, immunohistochemical analysis.
REFERENCES
1. Radzinskiy V.E. Akusherskaya agressiya [Aggression in obstetrics]. Moscow, Status Praesens Publ., 2011. 688 p.
2. Savitskiy A.G. The structure of uterine contractions anomalies in contemporary obstetrics: Clinical and statistical aspects. Zhurnal akusherstva i zhenskikh bolezney, 2005, vol. 54, no. 2, pp. 17-22. (in Russ.).
3. Sidorova I.S. Fiziologiya i patologiya rodovoy deyatel’nosti [Physiology and pathology of labor]. Moscow, MEDpress Publ., 2000. 320 p.
4. Prokhorenko R.I. Prognozirovanie i profilaktika anomaliy rodovoy deyatel’nosti u zhenshchin s soedinitel’notkannymi displaziyami. Kand. med. nauk diss. Avtoref. [Prediction and prevention of anomalies of labor in women with connective tissue dysplasia. Cand. med. sci. diss. Synopsis]. Kiev, 2010. 22 p.
5. Chan E.C., Fraser S., Yin S., Yeo G., Kwek K., Fairclough R.J., Smith R. Human myometrial genes are differentially expressed in labor: A suppression subtractive hybridization study. Journal of Clinical Endocrinology and Metabolism, 2002, vol. 87, no. 6, pp. 2435-2441. DOI:10.1210/jc.87.6.2435.
6. Yellon S.M., Mackler A.M., Kirby M.A. The role of leukocyte traffic and activation in parturition. Journal of the Society for Gynecologic Investigation, 2003, vol. 10, no. 6, pp. 323-338. DOI: 10.1016/S1071-5576(03)00116-3.
7. Chambers S., Pons J.C., Richard A., Chiesa M., Bouyer J., Papiernik E. Vaginal infections, cervical ripening and preterm delivery. European Journal of Obstetrics Gynecology and Reproductive Biology, 1991, vol. 38, no. 2, pp. 103-108.
8. Hagberg H., Mallard C., Jacobsson B. Role of cytokines in preterm labour and brain injury. BJOG: An International Journal of Obstetrics and Gynaecology, 2005, vol. 112, suppl. 1, pp. 16-18. DOI: 10.1111/j.1471-0528.2005.00578.x.
9. Maul H., MacKay L., Garfield R.E. Cervical ripening: Biochemical, molecular, and clinical considerations. Clinical Obstetrics and Gynecology, 2006, vol. 49, no. 3, pp. 551-563. DOI: 10.1097/00003081-200609000-00015.
10. Bowen J.M., Chamley L., Keelan J.A., Mitchell M.D. Cytokines of the placenta and extra-placental membranes: Roles and regulation during human pregnancy and parturition. Placenta, 2002, vol. 23, no. 4, pp. 257-273. DOI: 10.1053/plac.2001.0782.
11. Adeniji A.O., Olayemi O., Odukogbe A.A., Oladokun A., Adeniji O.I., Egbewale B.E., Omigbodun A.O. Cervico-vaginal foetal fibronectin: A predictor of cervical response at pre-induction cervical ripening. West African Journal of Medicine, 2005, vol. 24, no. 4, pp. 334-337.
12. Nesterenko Z.V. Classification concept of connective tissue dysplasia. Zdorov’e rebenka, 2010, no. 5 (26), pp. 11-13. (in Russ.).
13. Buyanova S.N., Savel’ev S.V., Grishin V.L., Senchakova T.N. Some aspects of genitalia prolapce pathogenesis. Akusherstvo i ginekologiya, 2001, no. 3, pp. 39-43. (in Russ.).