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  • Clinical case of listeriosis in a patient with Crohn’s disease

    Редактор | 2014, Practical medicine 04 (14) Innovative technologies in medicine. Part 1 | 30 июля, 2014

    A.Kh. ODINTSOVA1, L.R. SADYKOVA1, E.N. BELOUSOVA2, D.I. ABDULGANIYEVA2 

    1Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation. 420012

    2Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan, 138 Orenburgskiy Trakt, Kazan, Russian Federation, 420064 

    Odintsova A.Kh. — Cand. Med. Sc., Head of the Department of Gastroenterology, tel. (843) 237-36-27, e-mail: odincovaa@yandex.ru1

    Sadykova L.R. — gastroenterologist, tel. (843) 237-36-27, e-mail: odincovaa@yandex.ru1

    Belousova E.N. — resident doctor of the Department of Hospital Therapy, tel. +7-906-320-47-72, e-mail: vanilla16@mail.ru2

    Abdulganiyeva D.I. — D. Med. Sc., Head of the Department of Hospital Therapy, tel. +7-987-296-27-68, e-mail: diana_s@mail.ru2

    Increasing use of immunomodulator (IM) therapy and biological agents has remarkably improved disease management and the quality of life, but at the same time has increased the risk of infectious complications in patients with inflammatory bowel disease (IBD). These are infections caused by organisms that take advantage of a weakened immune system, and cause disease. Although these infections lead to high morbidity and mortality, only a minority of patients with IBD develop opportunistic infections. We need to screen, prevent, diagnose, and treat opportunistic infections in all patients with IBD. We present a clinical case of the patient with Crohn’s disease who developed severe listeriosis with meningitis.

    Key words: inflammatory bowel disease (IBD), listeriosis, opportunistic infections.

     

     

    REFERENCES

    1. Toruner M., Ed.V. Loftus Jr., Harmsen W.S., Zinsmeister A.R. Risk Factors for Op-portunistic Infections in Patients With Inflammatory Bowel Disease. Gastroenterology, 2008, vol. 134, pp. 929-936.

    2. Rahier J.F., Ben-Horin S., Chowers Y., Conlon C. et al. European evidence-based Consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease. Journal of Crohn’s and Colitis, 2009.

    3. Maneesh Dave, Raymund Razonable, Edward V. Loftus Jr. Opportunistic Infections Due to Inflammatory Bowel Disease. Inflamm Bowel Dis., 2014, vol. 20, pp. 196-212.

    4. Vázquez-Boland J.A., Kuhn M., Berche P., Chakraborty T. et al. Listeria Pathogenesis and Molecular Virulence Determinants. Clinical Microbiology revies, 2001, July, pp. 584-640.

    5. Camejo A., Carvalho F., Reis O. et al. The arsenal of virulence factors deployed by Listeria monocytogenes to promote its cell infection cycle. Virulence, 2011, vol. 2:5, pp. 379-394.

    6. Ramos J.M., García-Sepulcre M.F., Masiá M., Brotons A. et al. Listeria monocytogenes infection in patients with inflammatory bowel diseases receiving anti-tumor necrosis factor therapy. Revista Española de Enfermedades Digestivas, 2010, vol. 102, no. 10, pp. 614-616.

    Метки: A.Kh. ODINTSOVA, D.I. ABDULGANIYEVA, E.N. BELOUSOVA, inflammatory bowel disease (IBD), L.R. SADYKOVA, listeriosis, opportunistic infections, Practical medicine 04 (14) Innovative technologies in medicine. Part 1

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