L.N. VORONINA¹, E.S. GASILINA², S.M. KITAYCHIK¹, G.V. SANTALOVA², G.A. BUCHINA¹, N.A.VOLODINA³, O.V. BORISOVA², T.S. ANTIPOVA²

¹Samara City Hospital N 5, 222 Novo-Sadovaya Str., 443029 Samara, Russian Federation

²Samara State Medical University, 89 Chapaevskaya Str., 443099 Samara, Russian Federation

³Samara Regional Clinical Hospital named after V.D. Seredavin, 159 Tashkentskaya Str., 443095 Samara, Russian Federation

Voronina L.N. — physician of Advisory-diagnostic Center for persistent infections and parasitic infestations in children, tel. (846) 994-62-63, e-mail: lvoronina63@mail.ru

Gasilina E.S. — D. Med. Sc., Professor, Head of the Department of Children’s Infections, tel. +7-897-958-60-94, e-mail: gasilinaes@mail.ru

Kitaychik S.M. — Cand. Med. Sc., Associate Professor, Chief physician, tel. (846) 994-53-90, e-mail: mmugb5@samtel.ru

Santalova G.V. — D. Med. Sc., Professor, Head of the Department of Faculty Pediatrics, tel. +7-960-825-32-54, e-mail: galina.santalova@mail.ru

Buchina G.A. — Head of the 2^nd Department of Children’s Hospital, tel. (846) 994-72-01, e-mail: gabucha65@gmail.ru

Volodina N.A. — Head of the Department of Early Age Children, tel. (846) 959-25-88, e-mail: glav@sokb.ru

Borisova O.V. — D. Med. Sc., Associate Professor, Professor of the Department of Children’s Infections, tel. +7-927-205-53-79, e-mail: olgaborisova74@mail.ru

Antipova T.S. — clinical intern of the Department of Children’s Infections, tel. +7-987-158-76-46, e-mail: viola011@mail.ru

The article presents the results of observations of 355 children after acute Epstein-Barr virus infection. The issues of the epidemiology of this disease in children in the Samara region are discussed. The regional clinical features depending on the course of infection are studied. The dynamics shows the decline in the number of severe atypical forms. The severe atypical forms of EBVI often have no specific features, thus being hard to diagnose.

Key words: Epstein-Barr virus infection, children, epidemiology, clinical features.

REFERENCES

1. Bokovoy A.G., Egorov A.I. Gerpesvirusnye infektsii u detey i roditeley [Herpesvirus infection among children and parents]. Moscow: Tsentr strategicheskoy kon»yunktury, 2014. 256 p.

2. Infektsionnyy mononukleoz: klinika, novye podkhody k diagnostike i terapii u detey. Metodicheskoe posobie dlya vrachey, pod redaktsiey O.V. Rodionovoy i dr. [Infectious mononucleosis: clinical features, new approaches to diagnosis and treatment in children .Toolkit for doctors. Under the editorship of Rodionova O. et al.]. Saint Petersburg, 2000. 20 p.

3. Lobzin Yu.V., Ivanova V.V., Nasyrov R.A., Levina A.S., Babachenko I.V., Sharipova E.V. Clinical and etiological features of infectious mononucleosis in young children. Detskie infektsii, 2009, no. 1, pp. 20-23 (in Russ.).

4. Tolstikova T.V., Bregel’ L.V. Atypical form of Epstein – Barr virus infection in children. Sibirskiy meditsinskiy zhurnal, 2011, part 1, no. 6, pp. 113-115 (in Russ.).