Z.R. ASATULLINA¹, A.V. SINEGLAZOVA¹

 ¹Kazan State Medical University, Kazan

 Contact details:

Asatullina Z.R. — Assistant Lecturer of the Department of Policlinic Therapy and General Practice

Address: 49 Butlerov St., Kazan, Russian Federation, 420012, tel.: +7-987-208-93-92, e-mail: zemfira.nigmatullina96@gmail.ru

 The purpose — to analyze the comparability of liver ultrasound results and calculated indices of liver steatosis in asymptomatic individuals with non-alcoholic fatty liver disease (NAFLD) in a young age.

Material and methods. We examined 164 patients, including 80 men and 84 women aged Me = 35 [31–39] years old at Consultation and Diagnostic Center of Aviastroytelniy district of Kazan. The observational clinical case-control study was based on the criterion of constitutional obesity. The patients underwent anthropometry, measurement of blood pressure and blood insulin; indicators of lipid and carbohydrate metabolism were studied. An ultrasound examination of liver was performed to detect NAFLD. We calculated NAFLD-LFS, HIS, and TyG indices of liver steatosis. The data were processed with IBM SPSS Statistics 26.

Results. According to ultrasound data, NAFLD was found in 8.5% of the examined patients (n = 14). The frequency of increased values of all the studied indices, as well as the average values per se, were significantly higher in the group of people with liver steatosis according to ultrasound data compared with the group of people without steatosis (p = 0.000). When analyzing the ROC curves, statically significant results were obtained for all steatosis indices. The most sensitive and specific index was the HSI index.

Conclusion. The highest sensitivity and specificity when compared with ultrasound examination were established for the HSI hepatic steatosis index. The threshold value of the TyG index for liver steatosis was 4.57, which is lower than is accepted for the general population.

Key words: non-alcoholic fatty liver disease, steatotic liver disease, liver steatosis indices.

 (For citation: Asatullina Z.R., Sineglazova A.V. Calculated indices of liver steatosis in the practice of a primary care physician. Practical medicine. 2023. Vol. , № , P.)

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