YU.YU. FEDOROVA, A.S. KARUNAS, R.R. MURZINA, L.A. MUKHTAROVA, N.N. RAMAZANOVA, G.PH. GIMALOVA, R.PH. GATIYATULLIN, SH.Z. ZAGIDULLIN, E.I. ETKINA, E.K. KHUSNUTDINOVA
Institute of Biochemistry and Genetics, Ufa Scientific Center, Russian Academy of Sciences
Bashkir State University, Ufa
Bashkir State Medical University, Ufa

Fedorova Julia Yuryevna
Cand. Sc. (Biology), research associate of the laboratory of human molecular genetics of the Institute of Biochemistry and Genetics
71 Oktyabrya Ave., Ufa 450054
tel. (347) 235-60-88, e-mail: fedorova-y@yandex.ru

The analysis of ADRB2 gene polymorphisms rs1042713 (Arg16Gly) and rs1042714 (Gln27Glu) in patients with asthma and healthy individuals of Russian ethnicity from the Republic of Bashkortostan was conducted. The association of ADRB2*16Arg allele of Arg16Gly polymorphism with mildly decreased FEV1 (forced expiratory volume for 1 second) was revealed. There is no association between Gln27Glu polymorphisms in ADRB2 gene and asthma in Russians.

Key words: bronchial asthma, association, β2-adrenergic receptor gene.

 

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