S.V. ANDREYEV, N.P. SETKO, L.G. VORONINA

Orenburg State Medical Academy, 6 Sovetskaya St., Orenburg, Russian Federation, 460000 

Andreyev S.V. — postgraduate student of the Department of Hygiene and Epidemiology, tel. +7-922-621-46-55, e-mail: eeyy@mail.ru

Setko N.P. — D. Med. Sc., Professor, Head of the Department of Hygiene and Epidemiology, Vice Rector on Scientific and Clinical Work, tel. (3532) 77-62-21, e-mail: nauka@orgma.ru

Voronina L.G. — D. Med. Sc., Professor, Head of the Department of Dermatovenerology, tel. (3532) 56-03-52, e-mail: orenderm@mail.ru

The quality of life was assessed with questionnaire SF-36 v.2 in 250 patients with syphilis, during treatment and 1 month after therapy termination. It is shown than syphilis has heterogenic influence on quality of life depending on the disease stage. In patients with primary syphilis the effect was mainly on physical health, while in patients with early and late latent syphilis, and secondary syphilis — on the psychological component of health. The study showed a minor impact on the quality of life in patients with latent unspecified syphilis. A month after the treatment termination the quality of life almost recovered for all forms observed, except secondary syphilis, in which the reduction on the scale persisted (compared with the average for the population), reflecting the psychological component of health.

Key words: syphilis, quality of life, SF-36.

REFERENCES

1. WHO: Surveillance of the HIV/AIDS epidemic 2013 comprehensive package, available at: http://apps.who.int/iris/bitstream/10665/90893/1/9789241506298_eng.pdf, accessed: 08.04.2014.

2. European Centre for Disease Prevention and Control Annual: Epidemiological Report 2013, available at:http://ecdc.europa.eu/en/publications/Publications/annual-epidemiological-report-2013.pdf, accessed: 08.04.2014).

3. Kubanova A.A., Lesnaya I.N., Kubanov A.A., Melekhina L.E., Kaspirovich M.A. Analysis of the epidemiological situation and the dynamics of the incidence of infections, sexually transmitted diseases, and dermatoses in the territory of the Russian Federation. Vestnik dermatologii i venerologii, 2010, no. 5, pp. 4-21 (in Russ.).

4. Kungurov N.V., Ufimtseva M.A., Malishevskaya N.P., Syrneva T.A, Struin N.L., Surganova V.I. Epidemiological role of migrants in the spread of syphilis in the Urals, Siberia and the Far East. Vestnik dermatologii i venerologii, 2010, no. 2, pp. 4-9 (in Russ.).

5. Katunin G.L., Melekhina L.E., Frigo N.V. Neurosyphilis: epidemiology, pathogenesis, clinical features, laboratory diagnosis. Vestnik dermatologii i venerologii, 2013, no. 5, pp. 40-49 (in Russ.).

6. Kubanova A.A., Melekhina L.E., Kubanov A.A., Bogdanova E.V. The incidence of congenital syphilis in the Russian Federation during the 2002-2012 period. Vestnik dermatologii i venerologii, 2013, no. 6, pp. 24-31 (in Russ.).

7. Rodionov A.N. Sifilis [Syphilis]. Moscow: Piter, 2007.

8. Koupidis S., Nicolaidou E., Hadjivassiliou M., Bellos S., Skapinakis P., Stefanaki C., Papadogeorgakis H., Katsambas A. Health related quality of life in patients with anogenital warts, available at: http://www.hqlo.eom/content/9/7/67, accessed: 08.04.2014.

9. Voronova O.A., Gerasimova N.M. Scientific approaches to the study of the quality of life of patients with urogenital infections. Vestnik dermatologii i venerologii, 2009, no. 2, pp. 20-24 (in Russ.).

10. Kubanova A.A., Martynov A.A. The concept and definition of quality of life of patients in dermatovenerology. Vestnik dermatologii i venerologii, 2007, no. 6, pp. 14-18 (in Russ.).

11. Ware J.E., Kosinski M., Keller S.D. SF-36 Physical and Mental Health Summary Scales: A User`s Manual. The Health Institute, New England Medical Center. Boston, Mass., 1994, p. 150.

12. Amirdzhanova V.N., Goryachev D.V., Korshunov N.I., Rebrov A.P., Sorotskaya V.N. Population quality of life by SF-36 (results of a multicenter study of quality of life “MIRAZh”. Nauchno-prakticheskaya revmatologiya, 2008, no. 6, pp. 36-48 (in Russ.).

13. Delaryu V.V. Konkretnye sotsiologicheskie issledovaniya v meditsine [Specific case studies in medicine]. Volgograd, 2005.

14. Instruktsiya po obrabotke dannykh, poluchennykh s pomoshch’yu oprosnika SF-36 [Instructions for use of data obtained using SF-36 questionnaire], available at: http://www.preference-pro.com/files/sf-36_guidelines.pdf (accessed: 08.04.2014).