M.V. BURMISTROV^1-3, S.I. BEBEZOV^1,2, R.E. SIGAL¹, R.A. KHAZIEV¹

¹Tatarstan Cancer Center, 29 Sibirskiy Trakt, Kazan, Russian Federation, 420029

²Kazan State Medical Academy — Branch Campus of the RMACPE MOH Russia, 36 Butlerov Str., Kazan, Russian Federation, 420012

³ Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan, 138 Orenburgskiy Trakt, Kazan, Russian Federation, 420064

 Burmistrov M.V. ― D. Sc. (medicine), Professor of the Department of Oncology, Radiology and Palliative Medicine, Deputy Chief Physician for science, development and innovative technologies, e-mail: burma71@mail.ru, ORCID ID: 0000-0002-5334-6481

Bebezov S.I. ― postgraduate student of the Department of Oncology, Radiology and Palliative Medicine, surgeon of policlinic, e-mail: suleiman.bebezov@gmail.com, ORCID ID: 0000-0002-9312-9529

Sigal R.E. ― oncologist, Head of policlinic, e-mail: Rodion_sigal@mail.ru, ORCID ID: 0000-0002-3375-8542

Khaziev R.A. ― oncologist, Head of Admission Department №2, e-mail: rush2606@mail.ru, ORCID ID: 0000-0003-0571-1998

A comparative analysis of the quality of life of 2 groups of patients was performed: first group of patients with esophageal plastic of the gastric stem with esophagogastroanastomosis (EGA) on the neck, second group patients with esophageal plastic of the whole stomach with the formation of EGA in the right pleural cavity using a circular stapler. To assess the quality of life, we used questionnaires developed by the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 ver. 3.0 and QLQ — OES 24. 71 quality of life questionnaires were analyzed, 49 questionnaires of patients of the 1^st group and 22 questionnaires of patients of the 2^nd group. According to the questionnaire QLQ-C30, a statistically significant difference is found in the following indicators: emotional, cognitive and social functioning. These parameters were marked by higher rates in 2^nd group, which indicates a better quality of life in this group. Symptoms such as fatigue, pain, insomnia, loss of appetite were characterized by relatively high values in 1st group, which indicates a greater severity of these indicators in this group and the lower quality of life. However, when analyzing the QLQ-OES 24 questionnaire, there was no significant difference between the compared groups.

Key words: esophageal cancer, esophagus extirpation, quality of life, EORTC, QLQ — C30, QLQ — OES 24.

(For citation: Burmistrov M.V., Bebezov S.I., Sigal R.E., Khaziev R.A. Assessing the quality of life of patients after esophagus extirpation with various variants of gastric plastic. Practical Medicine. 2018)

REFERENCES

1. Ferlay J. et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int. J. Cancer, 2015, 136, pp. E359-E386.
2. Zlokachestvennye novoobrazovaniya v Rossii v 2016 godu (zabolevaemostʹ i smertnostʹ), pod red. A.D. Kaprina, V.V. Starinskogo, G.V. Petrovoy [Malignant neoplasms in Russia in 2016 (morbidity and mortality). Ed. By A.D. Kaprina, V.V. Starinsky, G.V. Petrova]. Moscow: MNIOI im. P.A. Gertsena ― filial FGBU “NMITS radiologii” Minzdrava Rossii, 2018. 250 p. ill.
3. Krylov N.N. Quality of life of patients as a problem of surgical gastroenterology. Ros. med. vestn, 1997, no.1, pp. 64-68 (in Russ.).
4. Novik A.A., Ionova T.I. Rukovodstvo po issledovaniyu kachestva zhizni v meditsine [Guide to the study of the quality of life in medicine]. Moscow, 2007.
5. Bammer T., Hinder R.A., Klaus A. et al. Safety and Long-term Outcome of Laparoscopic Antireflux Surgery in Patients in Their Eighties and Older. Surg. Endosc, 2002, vol. 16, no. 1, rr. 40-42.
6. Barbour A.P., Lagergren P., Hughes R. et al. Health-related Quality of Life Among Patients with Adenocarcinoma of the Gastroesophageal Junction Treated by Gastrostomy or Oesophagectomy. Br. J. Surg, 2008, vol. 95, no. 1, rr. 80-84.
7. Djarv T., Blazeby J.M., Lagergren P. Predictors of Postoperative Quality of Life after Esophagectomy for Cancer. J. Clin. Oncol, 2009, vol. 27, no. 12, rr. 1963-1968.
8. Shevchenko Yu.L., Novik A.A., Fedotov Yu.N. et al. nformation system for studying the quality of life in medicine. Vestn. Mezhnatsionalʹnogo tsentra issledovaniya kachestva zhizni, 2005, no. 5-6, pp. 4-9.
9. Fayers P.M., Asronson N.K., Bjordal K. et al. On behalf of the EORTC Quality of Life Study Group. The EORTC QLQ-C30 scoring manual. 3rd ed. Brussels: EORTC, 2001.