R.F. KHAKIMOVA¹, G.M. ZAYNETDINOVA², N.SH. KURMAEVA¹, О.А. SEREBRYAKOVA¹

 ¹Kazan State Medical University, Kazan

²Children’s Republican Clinical Hospital, Kazan

 Contact details:

Khakimova R.F. — MD, Professor of the Department of Clinical Immunology and Allergology

Address: 49 Butlerov St., Kazan, Russian Federation, 420012, tel.: +7 (843) 231-20-87, e-mail: Khakimova@yandex.ru

 Anaphylaxis is an acute life-threatening systemic reaction. The relevance of anaphylaxis in children, especially babies, is related to various clinical symptoms involving multiple organs and systems, particularly gastrointestinal system.

The purpose is a comparative analysis of 8 anaphylaxis cases in children.

Results. The clinical manifestations of anaphylaxis could be observed among patients in different age groups. Food allergy is the major elicitor of anaphylaxis in children. Anaphylaxis due to the cross-reactivity between pollen and food allergens is more frequent in children aged 6 to 9 years, whereas drugs and immunobiological preparations (vaccines) are the most leading triggers in adolescents. However, anaphylaxis in children is often under-diagnosed nowadays.

Key words: anaphylaxis, children, allergens, sensitization.

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