Algorithm of ultrasound investigation using compression sonoelastography in the diagnosis of ectopic pregnancy
N.A. VORONTSOVA1, V.E. GAZHONOVA1, I.S. BELOZEROVA1, S.O.CHURKINA1, O.V. KHITRYKH2, D.S. TITOV3
1Academic medical center at the Department for Presidential Affairs of the Russian Federation, 21 Marshala Timoshenko St., Moscow, Russian Federation 121359
2Central clinical hospital with polyclinic at the Department for Presidential Affairs of the Russian Federation, 15 Marshala Timoshenko St., Moscow, Russian Federation 121359
3Combined hospital with polyclinic at the Department for Presidential Affairs of the Russian Federation, 6 Michurinskiy Ave., Moscow, Russian Federation 119285
Vorontsova N.A. — postgraduate student at the Department of X-ray diagnostics, tel. (495) 530-06-72, +7-916-655-95-31, e-mail: www.vornad@bk.ru1
Gazhonova V.E. — Doctor of Medical Science, Professor at the Department of X-ray diagnostics, tel. (495) 530-00-19, e-mail: www.vx969@yandex.ru1
Belozerova I.S. — postgraduate student at the Department of X-ray diagnostics, tel. +7-910-414-59-91, e-mail: www.nibelozerov@yandex.ru1
Churkina S.O. — Candidate of Medical Science, assistant at the Department of X-ray diagnostics, tel. (495) 530-07-62, e-mail: www.14churkina@mail.ru1
Khitrykh O.V. — obstetrics and gynecology doctor, tel. +7-926-562-72-66, e-mail: www.alvoron@bk.ru2
Titov D.S. — obstetrics and gynecology doctor, tel. +7-916-298-49-31, e-mail: www.Ginekologija@rambler.ru3
The diagnostic algorithm at suspicion on ectopic pregnancy (EP) includes transvaginal ultrasonography and detection of the level of beta HCG in blood. The objective of the present research was the development of algorithm of ultrasound investigation with sonoelastography in 108 patients aged between 18 and 42 years hospitalized with suspected ectopic pregnancy. In all of the patients was determined the level of HC in urine and beta HCG in blood at the day of admission to hospital, ultrasound investigation in the standard B-mode and ultrasonic angiography, sonoelastography. The data of ultrasound examination were compared with the results of pathomorphological study of operating materials, obtained in the course of operational intervention. Statistical analysis of the research resultsprovided the following data: sensitivity of the diagnostic complex β-hCG + ultrasound investigation with compression sonoelastography — 90.4%, specificity — 81.7%, accuracy — 93.5%, a positive predictive test (PPT) — 96.5%, negative predictive test (OPT) — 86.3%. Considering the reproductibility of the technology of compression sonoelastography on the standard scale Kappa coefficient was 0,92.
Key words: sonoelastography, ectopic pregnancy.
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