T.V. CHERNYSHEVA¹, E.I. MALININA², O.A. RYCHKOVA²

¹Tyumen Cardiology Research Center ― branch of Tomsk National Research Medical Center of the Russian Academy of Sciences, 111 Melnikayte Str., Tyumen, Russian Federation, 625026

²Tyumen State Medical University, 54 Odesskaya Str., Tyumen, Russian Federation, 625023

 Chernysheva T.V. ― Cand. Med. Sc., Head of Children’s Department, e-mail: cardio72@rambler.ru

 The health status of children with hyperechogenic intracardiac focus (HEIF), visualized prenatally, was assessed. It is stated that in the postnatal period, HEIF is regressed in most cases. 24.8% of the prenatally visualized cases are visualized after birth; by the age of six months, 12.1% retain this syndrome, and by the age of 1 year ― 4.2%. Weak correlations of the after birth HEIF were found with the congenital heart disease (R=0.190, p=0.01) and structural defects of the internal organs (R=0.301, p<0.001). 88.9% children with prenatally diagnosed HEIF are characterized by the presence of small heart anomalies, which is statistically significantly higher than in the control group (p=0.016) and reflects the morphogenesis disorder in connective tissue in the fetal period. The ECG changes are determined in the first group more often than in the second one: incomplete right bundle-branch block (p<0.018), disorder of the ventricles repolarization processes (p<0.03). Posthypoxic cerebral ischemia (p=0.006) and anemia (p=0.05) are diagnosed in children with HEIF statistically significantly more often. New data on the prognostic significance of the «golf ball» ultrasound phenomenon have been obtained, and an algorithm for antenatal and postnatal observation of children with HEIF has been presented.

Key words: hyperechogenic intracardiac focus (HEIF), small abnormalities of cardiac development, posthypoxic cardiopathy, chronic intrauterine hypoxia.

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