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  •  Acute hemorrhagic leukoencephalitis: a case report

    Редактор | 2019, Clinical case, Practical medicine part 17 №7. 2019 | 20 ноября, 2019

    T.R. GALIULLIN1, L.R. SHARAPHUTDINOVA2, E.N. KHASANOVA2, E.N. ZAKIROVA2, O.V. LYUTOV2, V.F. TUNIK1, 2, K.Z. BAKHTIYAROVA1, 2

     1Bashkir State Medical University of the Ministry of Health of the Russian Federation, Ufa

    2Republican Clinical Hospital named after G.G. Kuvatov, Russian Federation, Ufa

     Contact details:

    Galiullin T.R. — postgraduate student of the Department of Neurology

    Address: 3 Lenina St., Ufa, Russian Federation, 450008, tel.: +7-962-547-41-07, e-mail: trgaliullin@mail.ru

    The purpose — to present a case of acute hemorrhagic leukoencephalitis — a malignant variant of acute disseminated encephalomyelitis.

    Material and methods. The case history, the results of clinical and additional methods of examination, magnetic resonance imaging of the brain, cytological and immunological studies of cerebrospinal fluid, as well as the results of a pathomorphological study of a patient observed in the Republican Clinical Hospital named after G.G. Kuvatov, Ufa, in May 2018, were studied.

    Results. A clinical case of a 54-year-old woman with hyperthermia in the onset of the disease, followed by the development of general cerebral symptoms, is presented. Magnetic resonance signs of multifocal leukoencephalopathy with subarachnoid and subcortical hemorrhages were revealed. Despite the ongoing intensive care, a fatal outcome occurred a month later from the first symptoms. The pathological study confirmed the clinical diagnosis.

    Conclusion. The described case of acute hemorrhagic leukoencephalitis confirms the aggressive nature of the course of this pathology and will serve as an accumulation of knowledge for the timely diagnosis of this rare pathology.

    Key words: acute hemorrhagic leukoencephalitis. 

    (For citation: Galiullin T.R., Sharaphutdinova L.R., Khasanova E.N., Zakirova E.N., Lyutov O.V., Tunik V.F., Bakhtiyarova K.Z.. Acute hemorrhagic leukoencephalitis: a case report. Practical Medicine. 2019. Vol. 17, № 7, P. 163-166)

    REFERENCES

    1. Duggal N., Ahmed I., Duggal N. Acute hemorrhagic leukoencephalitis associated with autoimmune myopathy. J Vasc Interv Neurol, 2014, vol. 7 (4), pp. 19–22.
    2. Khademi G.R., Aelami M.H. Acute hemorrhagic leukoencephalitis in children: a case report. Iran J Med Sci, 2016, vol. 41 (3), pp. 245–248.
    3. Lann M.A., Lovell M.A., Kleinschmidt-DeMasters B.K. Acute hemorrhagic leukoencephalitis: a critical entity for forensic pathologists to recognize. Am J Forensic Med Pathol, 2010, vol. 31 (1), pp. 7–11.
    4. Ryan L.J., Bowman R., Zantek N.D. et al. Use of therapeutic plasma exchange in the management of acute hemorrhagic leukoencephalitis: a case report and review of the literature. Transfusion, 2007, vol. 47 (6), pp. 981–986.
    5. Maratkanova T.V., Denisova G.A., Vostrikova I. L. cute hemorrhagic leukoencephalitis Hirst. Al’manakh klinicheskoy meditsiny, 2001, no. 4, pp. 225–226 (in Russ.).
    6. Schettino S., Caranci F., Lus G. et al. Diffuse glioblastoma resembling acute hemorrhagic leukoencephalitis. Quant Imaging Med Surg, 2017, vol. 7 (5), pp. 592–597.
    7. Panchal A., Perez-Marques F. Intravenous immunoglobulin for acute hemorrhagic leukoencephalitis refractory to plasmapheresis. Clin Case Rep, 2018, Nov. 28, vol. 7 (1), pp. 160–163.

    Метки: 2019, acute hemorrhagic leukoencephalitis, E.N. KHASANOVA, E.N. ZAKIROVA, K.Z. BAKHTIYAROVA, L.R. SHARAPHUTDINOVA, O.V. LYUTOV, Practical medicine part 17 №7. 2019, T.R. GALIULLIN, V.F. TUNIK

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