M.B. MUKANOVA¹, F.YU. KOPYLOV ², R.N. KOMAROV², I.I. SEREBRENNIKOV¹, F.S. GAFUROV ³, A.N. KHUZIAKHMEDOV², N.M. BABAKULOVA², A.M. ISMAILBAEV²

 ¹Moscow Regional Ambulance Facility, Krasnogorsk

²I.M. Sechenov First Moscow State Medical University, Moscow

³Egoryevsk Central Regional Hospital, Egoryevsk

 Contact details:

Mukanova M.B. — Head of Balashikha branch of Ambulance Facility

Address: 3 Znamenskaya St., Krasnogorsk, Russian Federation, 143400, tel.: +7-926-451-04-95, е-mail: mmaruar@mail.ru

 The purpose — to assess the acute coronary syndrome (ACS) clinical aspects in patients with aortic stenosis.

Material and methods. This is a retrospective single-center study that included comparison of hospital and midterm outcomes of ACS and aortic stenosis (n = 95, divided into the following groups: group 1 — severe aortic stenosis + ACS (n = 39); group 2 — moderate aortic stenosis + ACS (n = 28); group 3 — ACS without aortic stenosis (the control group selected using «Propensity matching» method) (n = 28)).

Results. Hospital mortality did not differ statistically between the groups. In group 1, there was a tendency to worse survival within 1 year. In groups with aortic malformation, ACS with ST segment elevation was less common — p = 0.0002 and p = 0.001, respectively. In group 1, 23.1% of patients had intact coronary arteries.

Conclusions. Severe aortic valve stenosis in some cases «mimics» acute coronary syndrome, which is indicated by significantly more frequent detection of intact coronary arteries in this cohort. Aortic stenosis of varying degrees does not lead to an increase in the frequency of early postoperative complications and 30-day mortality after PCI.

Key words: acute coronary syndrome, aortic stenosis, percutaneous coronary interventions, clinical outcomes.

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