T.A. SHAIMOVA¹, I.E. PANOVA², V.A. SHAIMOVA³

¹«TSENTR ZRENIYA», 88 Komsomolskiy Ave., Chelyabinsk, Russian Federation, 454014

²The Saint Petersburg Branch of the S. Fyodorov Eye Microsurgery Federal State Institution, 21 Yaroslav Gashek Str., St. Petersburg, Russian Federation, 192283.

³Chelyabinsk State Institute of Laser Surgery, 287 Pobedy Ave., Chelyabinsk, Russian Federation, 454018

Shaimova T.A. ― Competitor of the Ophthalmology Department, Ophthalmologist, tel. +7-951-777-11-53, e-mail: tanja.shaimova@gmail.com

Panova I. E. ― D. Med. Sc., Professor, Deputy Director for scientific work, tel. +7-906-890-28-68, e-mail: eyeren@yandex.ru

Shaimova V. A. ― D. Med. Sc., Chief Physician, leading researcher, tel. +7-950-744-49-45, e-mail: shaimova.v@mail.ru

A comparative analysis of parameters of chorioretinal complex in patients with combined pathology ― age-related macular degeneration (AMD) and primary open angle glaucoma (POAG) is performed. The study was conducted by optical coherence tomography (OCT) in three study groups (SG): SG1 ― 38 patients (65 eyes) with combined pathology ― AMD, dry form and POAG; SG2 ― 37 patients (62 eyes) with AMD, the dry form; SG3 ― 27 patients (48 eyes) with POAG. In SG1 and SIG2 were made two subgroups: A ― atrophic form of AMD (1A and 2A); B ― macula druzen (1B and 2B). Test parameters: neuroepithelium thickness (NT), the layer thickness of retinal ganglion cells (RGCs), thickness of choroid. The index of thickness of retinal ganglion cells (TRGCs) = the thickness of RGCs / thickness of NT is calculated. The distinguishing characteristics of OCT parameters of chorioretinal macular area in SG1 patients are given: reduced thickness of NE (p<0,001) in comparison with the control group, to a greater extent in SG1A (p<0,001); thickness of the RGCs and values of TRGCs index decreased in comparison with the control group (p<0,001), SG2A and SG2B (p<0,05); thickness of NT, RGCs layer and RGCs index have an inverse correlation (p<0,001) with stage of POAG and decrease with an increase in POAG stage; choroidal thickness is reduced, to a greater extent in SG1A, compared with the control group (p<0,001), a subgroup of patients SG2B and SG3. It can be assumed that the presence of concomitant diseases in the form of POAG in a patient with AMD makes possible the flow of macular degeneration with progressive atrophic form due to violations of the trophism of the neurosensory retina.

Key words: age-related macular degeneration, primary open-angle glaucoma, optical coherence tomography.

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