T.P. ZEPHIROVA¹, L.I. MALTSEVA¹, R.S. ZAMALEYEVA², M.E. ZHELEZOVA¹, N.Yu. CHISTYAKOVA²

¹ Kazan State Medical Academy — Branch Campus of the RMACPE MOH Russia, 36 Butlerov Str., Kazan, Russian Federation, 420012

² Kazan (Volga) Federal University, 1A Chekhov Str., Kazan, Russian Federation, 420020

 Syndrome of thrombotic micro-angiopathy in life-threatening complications of pregnancy and labor in women

 Zephirova T.P. — D. Med. Sc., Professor of the Department of Obstetrics and Gynecology No. 1, tel. +7-987-290-45-99, e-mail: tzerirova@gmail.com

Maltseva L.I. — D. Med. Sc., Professor, Head of the Department of Obstetrics and Gynecology No. 1, tel. +7-905-314-40-51, e-mail: laramalc@mail.ru,

Zamaleeva R.S. — D. Med. Sc., Professor of the Department of Obstetrics and Gynecology No. 1, tel. +7-919-621-67-51, e-mail: zamaleewa@rambler.ru

Zhelezova M.E. — Cand. Med. Sc., Associate Professor of the Department of Obstetrics and Gynecology No. 1, tel. +7-919-627-13-66, e-mail: gelezovam@gmail.com

Chistyakova N.Yu. — Cand. Med. Sc., Head of the Maternity Department, tel. +7-987-296-86-32, e-mail: ninadoc@rambler.ru

 The article presents the data on thrombotic micro-angiopathy (TMA), the basis of which is lesion of micro-circulation vessels with microthrombi in capillary and arteriole lumen, thrombocytopenia, micro-angiopathological hemolytic anemia and multiple organ failure. It is shown that TMA syndrome can develop in various pathology in obstetric practice, requiring different approaches to therapy. The authors’ clinical observation of TMA syndrome in a woman in labor is presented.

Key words: complications of pregnancy, thrombotic micro-angiopathy, diagnostics, therapy.

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