Ectopic activity of a myocardium in heart failure in the aspect of ion-transport function of a cell membrane
O.V. BULASHOVA¹, E.G. SLEPUKHA², V.N. OSLOPOV¹
1Kazan State Medical University, 49 Butlerov Str., Kazan, Russian Federation, 420012
2Municipal Clinical Hospital No. 7, 54 Chuikov Str., Kazan, Russian Federation, 420103
Bulashova O.V. ― D. Med. Sc., Professor of the Department of Propedeutics of Inner Diseases, tel. (843) 296-14-03, e-mail: boulashova@yandex.ru
Slepukha E.G. ― Cand. Med. Sc., Assistant Lecturer of the Department of Propedeutics of Inner Diseases, Head of the Department of Emergency Cardiology, tel.: +7-903-340-08-09, e-mail: slepuha_elena@mail.ru
Oslopov V.N. ― D. Med. Sc., Professor, Head of the Department of Propedeutics of Inner Diseases, tel. +7-905-316-23-35, e-mail: kpvbol@yandex.ru
The article presents the results of examination of 60 patients with chronic heart failure at the compensation stage who underwent Holter ECG monitoring. The cell membrane iontransportation function was estimated by determining the maximum speed of Na+/Li+ ― countertransport in the erythrocyte membrane. The data reveals high incidence of supraventricular ― 98.33 % and ventricular ― 75 % ― arrhythmias not depending on the severity of functional disorders. The ventricular rhythm disorders ― high grade extrasystole (by B. Lown and M. Wolf) was characteristic for patients with low-speed of Na+/Li+ ― countertransport in the erythrocyte membrane.
Key words: chronic heart failure, ventricular extrasystole, speed of Na+/Li+— countertransport.
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