S.V. MALTSEV¹, N.V. RYLOVA²

¹Kazan State Medical Academy, 36 Butlerov St., Kazan, Russian Federation, 420012

²Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation, 420012

Maltsev S.V. — D. Med. Sc., Professor, Head of the Department of Pediatrics with the course of outpatient pediatrics, tel. (843) 236-20-84, e-mail: [email protected]

Rylova N.V. — D. Med. Sc., Professor of the Department of hospital pediatrics with courses of postgraduate education and further vocational education, tel. +7-917-039-733-93, e-mail: [email protected]

This article presents the current domestic and foreign studies of vitamin D. In recent years there were received new data on assessing the role of vitamin D for the prevention and the course of a number of common diseases of a modern man. In this article consideration is given to peculiarities of its metabolism and function, the effect on the immune system. The present data indicate that vitamin D inhibits adaptive immunity, but contributes to innate. This vitamin inhibits cell proliferation, herewith stimulates cell differentiation. However, the mechanisms of action of vitamin D on the immune system and its therapeutic potential in case of pathology require further investigation.

Key words: vitamin D and its functions, vitamin D receptors, immunity.

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