S.A. LISOVSKAYA, E.V. KHALDEEVA, N.I. GLUSHKO

Kazan Research Institute of Epidemiology and Microbiology, 67 Bolshaya Krasnaya Str., Kazan, Russian Federation, 420015

Lisovskaya S.A. ― Cand. Med. Sc., Leading Researcher of the Mycology Laboratory, tel. (843) 236-56-59, e-mail: [email protected]

Khaldeeva E.V. ― Cand. Med. Sc., Head of the Mycology Laboratory, tel. (843) 236-56-59, e-mail: [email protected]

Glushko N.I. ― Senior Researcher of the Mycology Laboratory, tel. (843) 236-56-59, e-mail: [email protected]

The virulence features (adhesion) was studied of 6 strains of Candida albicans taken from patients with various candidosis forms. Influence of associated bacteria is estimated using extracts of S. aureus. It was established that adhesion of mucosal strains is 1.5-3 times higher than that of the skin strains. The obtained results show that differences in adhesive properties of C. albicans strains are associated with mycosis localization. Cultivation of C. albicans cultures with extracts of bacteria during 2 days twice increases virulence features of C. albicans. Thus, it is shown that virulence features of C. albicans may increase under the influence of associated bacteria during their collective growth and more serious forms of candidiasis may occur.

Key words: Candida albicans, adhesion, pathogenity, candidiasis associated bacteria, antagonism.

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