T.P. ZEPHIROVA¹, L.I. MALTSEVA¹, R.S. ZAMALEYEVA², M.E. ZHELEZOVA¹, N.Yu. CHISTYAKOVA²

¹ Kazan State Medical Academy — Branch Campus of the RMACPE MOH Russia, 36 Butlerov Str., Kazan, Russian Federation, 420012

² Kazan (Volga) Federal University, 1A Chekhov Str., Kazan, Russian Federation, 420020

 Zephirova T.P. — D. Med. Sc., Professor of the Department of Obstetrics and Gynecology No. 1, tel. +7-987-290-45-99, e-mail: [email protected]

Maltseva L.I. — D. Med. Sc., Professor, Head of the Department of Obstetrics and Gynecology No. 1, tel. +7-905-314-40-51, e-mail: [email protected],

Zamaleeva R.S. — D. Med. Sc., Professor of the Department of Obstetrics and Gynecology No. 1, tel. +7-919-621-67-51, e-mail: [email protected]

Zhelezova M.E. — Cand. Med. Sc., Associate Professor of the Department of Obstetrics and Gynecology No. 1, tel. +7-919-627-13-66, e-mail: [email protected]

Chistyakova N.Yu. — Cand. Med. Sc., Head of the Maternity Department, tel. +7-987-296-86-32, e-mail: [email protected]

 The article presents the data on thrombotic micro-angiopathy (TMA), the basis of which is lesion of micro-circulation vessels with microthrombi in capillary and arteriole lumen, thrombocytopenia, micro-angiopathological hemolytic anemia and multiple organ failure. It is shown that TMA syndrome can develop in various pathology in obstetric practice, requiring different approaches to therapy. The authors’ clinical observation of TMA syndrome in a woman in labor is presented.

Key words: complications of pregnancy, thrombotic micro-angiopathy, diagnostics, therapy.