E.E. IOYLEVA¹, M.S. KRIVOSHEEVA²

¹S. Fyodorov Eye Microsurgery Federal State Institution, 59а Beskudnikovsky Blvd, Moscow, Russian Federation, 127486

²Sergiev Posad District Hospital, 62a Novouglichskoye shosse, Sergiev Posad, Russian Federation, 141301

 Ioyleva E.E. ― D. Sc. (medicine), scientific secretary, Professor of the Department of Ophthalmology of Moscow State University for Medicine and Dentistry named after A.I. Evdokimov, tel. (499) 488-85-24, e-mail: [email protected]

Krivosheeva M.S. ― ophthalmologist of the Surgical Department, e-mail: [email protected]

The article deals with the aspects of diagnostic significance of the complex of retinal ganglion cells and the inner plexiform layer in patients with optic neuritis in the manifestation of multiple sclerosis using spectral optical coherence tomography. The research showed a reduction in the thickness of the complex of retinal ganglion cells and the inner plexiform layer to 76.23 μm in the group with optic neuritis due to MS compared with normal indices (82 μm). This indicator can be regarded as a marker of early diagnosis of multiple sclerosis. Thus, revealing a decrease in the thickness of ganglion cells of the retina may indicate the demyelinating nature of ON under further development of optic atrophy during the disease manifestation.

Key words: optic neuritis, multiple sclerosis, spectral optical coherence tomography, retinal ganglion cell complex and inner plexiform layer

(For citation: Ioyleva E.E., Krivosheeva M.S. Significance of assessment of neuroarchitectonics of the retina under optic neuritis. Practical Medicine. 2018)

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