N.V. RULOVA¹, S.V. MALTSEV¹, A.V. ZHOLINSKIY²

¹Kazan State Medical University of the Ministry of Health of the Russian Federation

²Federal Scientific and Clinical Center for Sports Medicine and Rehabilitation of Federal Medical and Biological Agency

 Address for correspondence:

Rulova N.V. – D. Med. Sc., Professor of the Department of Hospital Pediatrics of Kazan State Medical University of the Ministry of Health of the Russian Federation, 49 Butlerov Str., Кazan, Russian Federation, 420012

 Numerous publications point to a number of positive effects of vitamin D for people of all ages. Until recently, vitamin D deficiency was associated mainly with the risk of developing rickets. In recent years in studying the role of vitamin D in the prevention and progress of a number of widespread diseases of modern man extremely important data have been obtained. Features of its metabolism and function, influence on the immune system are considered. The currently available data indicate that vitamin D inhibits adaptive immunity, but contributes to innate. It inhibits cell proliferation, herewith it stimulates cell differentiation. However, the action mechanisms of Vitamin D on the immune system and its therapeutic potential in the presence of a disease require further study.

Key words: vitamin D and its functions, vitamin D receptors, immunity.

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