S.Yu. AKHUNOVA, T.A. BARSUKOVSKAYA, A.Yu. RAFIKOV, G.B. SAYFULLINA
Kazan State Medical Academy — Branch Campus of the FSBEI FPE RMACPE MOH Russia, 36 Butlerov Str., Kazan, Russian Federation, 420012

Interregional Clinical Diagnostic Center, 12A  Karbysheva Str., Kazan, Russian Federation, 420101

Contact:

Akhunova S.Yu. — Cand. Med. Sc., Associate Professor of the Department of Functional Diagnostics, Head of the Functional Diagnostics Department, tel. (843) 291-11-30, e-mail: akhunova@gmail.com

Barsukovskaya T.A.— doctor of the Department of Functional Diagnostics, tel. (843) 291-11-30, e-mail: barrsya@mail.ru

Rafikov A.Yu.  — Cand. Med. Sc., doctor of the Radiology Department, tel. (843) 291-11-16, e-mail: alex_raf@mail.com

Sayfullina G.B. — doctor of Radio Isotope Diagnostics Laboratory, tel. (843) 291-11-24, e-mail: sayfullina_rad@mail.ru

 The article presents a literature review reflecting modern approaches to the diagnosis of cardiac amyloidosis. The variants of cardiac amyloidosis and the role of echocardiography in its diagnosis and echocardiographic criteria of cardiac amyloidosis are discussed, the possibilities and areas of application of other diagnostic methods are shown. The article is illustrated by authentic echocardiographic images.

Key words: echocardiography, cardiac amyloidosis, restrictive cardiomyopathy

REFERENCES

1. Diagnostika i lechenie AA i AL amiloidoza. Natsional’nye klinicheskie rekomendatsii [Diagnosis and treatment of AA and AL amyloidosis. National clinical recommendationss]. Nauchnoe obshchestvo nefrologov Rossii, 2014, available at: http://http://nonr.ru/?page_id=3178 (accessed: 16.02.2018)
2. Myasnikov R.P., Andreenko E.Yu., Kushunina D.V. et al. Amyloidosis of the heart: modern aspects of diagnosis and treatment. Klinicheskaya i eksperimental’naya khirurgiya, 2014, no. 4, pp. 72-82 (in Russ.).
3. Zhdanova E.A., Rameev V.V., Moiseev S.V. et al. Amilyoidoz of the heart. Klinicheskaya farmakologiya i terapiya, 2011, no. 20 (5), pp. 44-50 (in Russ.).
4. Lutay M.I., Golikova I.P., Tsyzh A.V., Bugaenko V.V. Amyloidosis of the heart: definition, diagnosis, treatment. Ukraїns’kiykardіologіchniy zhurnal, 2013, no. 1, pp. 124-138 (in Russ.).
5. Bulaeva N.I., Golukhova E.Z., Mashina T.V., Shumkov K.V. Amyloidosis of the heart: a clinical case and a literary reference. Kreativnaya kardiologiya, 2012, no. 2, pp. 85-89 (in Russ.).
6. Volkova E.N., Posnenkova O.M., Popova Yu.V., Kiselev A.R. A clinical case of a neglected form of primary amyloidosis with heart disease. Bulletin of Medical Internet Conferences, 2014, no. 4, I. 9, pp. 1038-1041 (in Russ.).
7. Amiloidosis: diagnosis and treatment, ed. by M.A. Gertz, S.V. Rajkumar. New York: Humana Press, 2010.
8. Dispor E., Bridu F., Sirak K. et al. AL-Amyloidosis. Nefrologiya, 2014, vol. 18, no. 4, pp. 36-50 (in Russ.).
9. Philippakis A.A., Rodney H.F. Cardiac amyloidosis Mimicking Hypertrophic Cardiomyopathy with obstruction. Circulation, 2012, no. 125, pp. 1821-1824.
10. Rapezzi C., Merlini G., Quarta C. et al. Systemic cardiac amiloidoses. Desease profiles and clinical courses of the 3 main types. Circulation, 2009, 120, pp. 1203-1212.
11. Phelan D., Collier P., Thavendiranathan P. et al. Relative ‘‘apical sparing’’ of longitudinal strain using 2-dimensional speckle-tracking echocardiography is both sensitive and specific for the diagnosis of cardiac amyloidosis. Heart, 2012, no. 98, pp. 1442-1448.
12. Stoodley P., Richards D. Cardiac amyloidosis: the value of myocardial strain echocardiography in diagnosis and treatment. Sonography, 2015, no. 2, pp. 32-38.
13. Prakticheskaya ekhokardiografiya: Rukovodstvo po ekhokardiograficheskoy diagnostike, pod red. F.A. Flakskampfa; pod obshch. red. V.A. Sandrikova [Practical echocardiography: A guide to echocardiographic diagnostics. Ed by. F.A. Flaxcampf; V.A. Sandrikov]. Moscow: MEDpress-inform, 2013. 872 p.
14. Alekhin M.N. Problems and prospects of echocardiographic evaluation of diastolic function of the left ventricle of the heart. Kardiologiya, 2017, no. 1, pp. 71-75 (in Russ.).
15. Mohty D., Petitalot V., Magne J. et al. Left atrial function in patients with light chain amyloidosis: A transthoracic 3D speckle tracking imaging study. J Cardiol, 2018, no. 71(4), pp. 419-427.
16. Foldeak D., Kormanyos A., Domsik P. et al. Left atrial dysfunction in light-chain cardiac amyloidosis and hypertrophic cardiomyopathy – A comparative three-dimensional speckle-tracking echocardiographic analysis from the MAGYAR-Path Study. Rev Port Cardiol, 2017, no. 36(12), pp. 905-913
17. Otto C.M. Textbook of clinical echocardiography. 5th ed. Philadelphia, PA.: Elsevier Saunders, 2013. 561 p.
18. Fontana M., Pica S., Reant P. et al. Prognostic Value of Late Gadolinium Enhancement Cardiovascular Magnetic Resonance in Cardiac Amyloidosis. Circulation, 2015, no. 132(16), pp. 1570-9.
19. Rohan I.D., Richard E.S., Wendy E.S. MR Findings in Cardiac Amyloidosis. AJR, 2006, no. 186, pp. 157–1685.
20. Syed I.S., Glockner J.F., Feng D. et al. Role of cardiac magnetic resonance imaging in the detection of cardiac amyloidosis. JACC Cardiovasc. Imaging, 2010, no. 3, pp. 155-164.
21. Bokhari S., Shahzad R., Castaño A., Maurer M.S. Nuclear imaging modalities for cardiac amyloidosis. J NuclCardiol, 2014, no. 21(1), pp. 175-184.
22. Kumar S., Dispenzieri A., Lacy M. et al. Revised Prognostic Staging System for Light Chain Amyloidosis Incorporating Cardiac Biomarkers and Serum Free Light Chain Measurements. J ClinOncol, 2012, no. 30(9), pp. 989–995.